Session Information
Date: Tuesday, September 24, 2019
Session Title: Parkinsonisms and Parkinson-Plus
Session Time: 1:45pm-3:15pm
Location: Agora 3 West, Level 3
Objective: The main objective of this study is set as to determine the relationship between several Functional Mobility Tests (FMT) and disease stages in patients with Parkinson’s disease (PD).
Background: PD is a progressive neurodegenerative disorder which is characterized with motor and non-motor symptoms. One of the most disabilitating symptoms in PD is balance disorder as it may cause falls related secondary injuries; resulting with great reduction in quality of life and self sufficiency in activities of daily living. Functional Mobility Tests (FMT) which are used often and practically in clinical settings may give us an idea about balance in patients with PD. There are several FMTs to assess functional mobility in patients with PD and they correlate in different levels with disease stages. Therefore there is a need to detect association levels between FMTs and disease stages in patients with PD.
Method: This study is planned as a cross-sectional study. Functional mobility was assessed with 10 meter walk test at maximum speed (10MWT-max), 10MWT at normal speed (10MWT-normal) timed up and go test (TUG), timed up and go test with a dual task (reverse counting) (TUG-cog), 6 minutes walk test (6MWT). Disease stage was assessed using Modified Hoehn and Yahr Disease Staging (MH&Y). Kolmogrov Smirnov analysis and histogram graphic showed that data did not distributed normally. Hence, Spearmann correlation coefficient was determined to detect association between FMTs and disease stages.
Results: A total of 42 patients were evaluated. Correlations between MH&Y and 10MWT-max 10MWT-normal, TUG, TUG-cog, 6MWT were calculated. Correlation coefficients were found in order; 0.571 (p<0.001), 0.596 (p<0.001), 0.553 (p<0.001), 0.492 (p<0.001), -0.665 (p<0.001). As seen, all FMTs correlated significantly with MH&Y stages. 6MWT has a slightly higher correlation (strong) with disease stage while others have moderate.
Conclusion: The results of this study showed that all popular, clinically used FMTs correlated significantly in moderate to high levels with disease stage assessed with MH&Y. While 6MWT correlated strongly with MH&Y; 10MWT-max, 10MWT-normal, TUG, TUG-cog correlated moderately.
To cite this abstract in AMA style:
B. üğüt, T. Kahraman, A. Kalkan, A. Genç, B. çolakoğlu. Functional mobility tests and their relationship with disease stage in patients with Parkinson’s Disease [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/functional-mobility-tests-and-their-relationship-with-disease-stage-in-patients-with-parkinsons-disease/. Accessed June 14, 2025.« Back to 2019 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/functional-mobility-tests-and-their-relationship-with-disease-stage-in-patients-with-parkinsons-disease/