Category: Parkinson's Disease: Non-Motor Symptoms
Objective: Presence of impulse control behaviour (ICB) was assessed in PRISM, a European survey of people with Parkinson’s disease (PwP) and their care-partners.
Background: Impulse control disorders are part of behavioural disturbances in PwP and may result in serious financial and psychosocial consequences [1,2].
Method: PRISM was a descriptive, exploratory, observational study with cross-sectional design fielded through an online survey developed in collaboration with The Cure Parkinson’s Trust (UK-based advocacy group) and an international scientific committee. Collecting data through online channels may limit results interpretation. ICBs were recorded as yes/no answers to the question “are any of the behaviours listed an issue for you, or do others think that you have an issue?”. Behaviours included pathological gambling, hypersexuality, compulsive shopping, binge-eating, overuse of antiparkinsonian medications and hobbyism. Data were assessed in relation to patient characteristics, including dopamine agonist (DA) use and presence of comorbid depression/anxiety.
Results: Between April-July 2019, data were collected from 861 PwP from six European countries. Overall, approximately 45% of PwP reported at least one ICB (Figure 1). All ICBs were more frequently reported in PwP currently taking DA versus those who had never taken DA (Figure 1). PwP diagnosed with comorbid depression (22%) or anxiety (16%) were more likely than other PwP to report ICBs relating to eating, shopping, overuse of antiparkinsonian medications and hobbyism (Figure 2).
Conclusion: PRISM highlights relevance and range of ICBs in PwP and reinforces its association with DA use, mood and anxiety.
References: 1. Gatto EM, Aldinio V. Front Neurol.2019;10:351. 2. Rodríguez-Violante M, Antonini A. Front Neurol.2019;10:972.
To cite this abstract in AMA style:
A. Antonini, E. Tolosa, J. Ferreira, A. Lees, T. Foltynie, G. Ebersbach, O. Rascol, J.F Rocha, D. Magalhães, P. Soares-da-Silva. Impulse Control Behaviours in People with Parkinson’s Disease: Findings from the Parkinson’s Disease Real-World Impact Assessment (PRISM) Study [abstract]. Mov Disord. 2020; 35 (suppl 1). https://www.mdsabstracts.org/abstract/impulse-control-behaviours-in-people-with-parkinsons-disease-findings-from-the-parkinsons-disease-real-world-impact-assessment-prism-study/. Accessed June 15, 2025.« Back to MDS Virtual Congress 2020
MDS Abstracts - https://www.mdsabstracts.org/abstract/impulse-control-behaviours-in-people-with-parkinsons-disease-findings-from-the-parkinsons-disease-real-world-impact-assessment-prism-study/