Objective: The aim was to determine the epidemiologic, clinical and therapeutic aspects of patients treated for PD.

Methods: This was a prospective and cross-sectional study conducted over 12 months on 21 patients treated for Parkinson’s disease at the Neurology department of Tashkent. The data have been collected using a pre-established form for the survey.

Results: Sex ratio was 13/8 and the mean age was 60.26 ±1.7 years. The Uzbek population was the most represented ethnic group with 47.36%. 68.42% were married. 21.05% were farmers and 63.15% had achieved the primary level education. Consanguinity was found in 42.12% cases and the use of pesticides was noted in 15.78%. The average age of onset was around 55.42 ±1.6 years. Tremor was the first functional sign (68.42%) and was present in 84.21% of patients. However, rigidity was found in 94.73% of them. The other signs were represented by motor fluctuations (79.84%), painful syndrome (72.57%), mood disorder (53.51%), hallucinations (41.13%), sleep disturbances (32.57%). Brain CT was available in five patients and was normal in four of them. 36.84% of the patients were receiving only (Levodopa + benserazide or carbidopa) or piribedil and 52.63% one of these in association with Trihexyphenidyl. 42.10% were benefiting of physiotherapy.

Conclusions: Frequency of PD signs in our setting is not different from those in western countries. It is important to educate general practitioners and people for early recognition of PD signs for a better management.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/movement-disorders-parkinsons-disease-in-uzbekistan-epidemiologic-clinical-and-therapeutic-aspects/