Session Time: 12:00pm-1:30pm
Location: Exhibit Hall located in Hall B, Level 2
Objective: To evaluate the cognitive profile in a cohort of patients with Parkinson’s disease (PD) using a standardised battery.
Background: Cognitive impairment is a great challenge in patients with Parkinson´s Disease (PD). The variation in tools used for cognitive evaluation is an additional problem in this population.We present a neuropsychological assessment in a PD population using a standardized battery based on Movement disorders Society recommendations.
Methods: Consecutive PD patients according to London Barin Bank Criteria were evaluated extensively for different cognitive domains (attention, memory, language, executive functions and processing speed) and depressive symptoms using an stndarized battery. Cognitive impairment was diagnosed according to MDS criteria.
Results: Twenty five patients were included. Age (mean+/-SD) was 60.8±11.7 years, 28% were females. PD evolution was between 2 and 15 years. Alterations in at least one neuropsychological test were present in 100% of subjects. Dementia was diagnosed in 18% of patients, whereas mild cognitive impairment was present in 36% of the cases. Dementia was present in 60% of those older than 70 years. MoCA test was affected in 80% of cases (Z: -2.6±1.9). AVLT (Episodic auditive verbal memory) was altered in 84% of subjects (Z: -3,8±2.0). BVMT (Visuospatial memory) was affected in 44% of patients (Z: -1,4±0.9). Boston test (semantic memory) was altered in 40 subjects (Z:-1.1±1.2). TMT-A (visual attention) was altered in 32% of cases (Z: 0,6±2.4). Digit Span (Auditive attention) was affected in 32% of patients (Z: -0.4±1.8). SDMT (Processing speed) was altered in 24% of cases (Z:-0.4±1.0). FAS (cognitive alternancy) was affected in 28% of subjects (Z:-0.5±1.4). The tower test of D-KEFS was altered in 20%, (Z:-0,5 ± 1.4). Depressive symptoms were found in 53% of patients.
Conclusions: We found a high percentage of cognitive alterations in our PD population. Both verbal and visual episodic memories were affected in 50% of patients. As previously reported, older patients were more affected by dementia. FONDECYT Nº 11130534.
XII World Congress of Neurology.
To cite this abstract in AMA style:C. Juri, W. Uslar, H. Farias, M. Vasquez. Neuropsychological assessment in a cohort of patients with Parkinson’s disease [abstract]. Mov Disord. 2016; 31 (suppl 2). https://www.mdsabstracts.org/abstract/neuropsychological-assessment-in-a-cohort-of-patients-with-parkinsons-disease/. Accessed September 21, 2023.
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MDS Abstracts - https://www.mdsabstracts.org/abstract/neuropsychological-assessment-in-a-cohort-of-patients-with-parkinsons-disease/