Clinical Characteristics and Functional Impact of Tremor in Patients with Multiple Sclerosis in Nepal: A Cross-Sectional Observational Study
Objective: To describe the clinical characteristics of tremor in multiple sclerosis (MS) patients in Nepal and assess its functional impact on daily living. To describe…The Correlation Between Serum Uric Acid Levels And The Severity Of Parkinson’s Disease
Objective: This study aims to analyze the correlation between serum uric acid levels and the severity of Parkinson's disease. Background: Uric acid has been implicated…Quantitative Analysis of Oculomotor Abnormalities in Parkinson’s Disease
Objective: To quantitatively characterize oculomotor abnormalities in patients with Parkinson’s disease (PD) and to evaluate their potential utility for assessing oculomotor dysfunction and supporting early…Repurposing Rifabutin for Neuro-Metabolic Disorders: AMPK-PGC-1α-Driven Mitochondrial Protection in Diabetes Associated Parkinsonism
Objective: To assess the role of rifabutin in restoring mitochondrial function and energy balance through modulation of the AMPK–PGC-1α signaling pathway in diabetes-related Parkinsonism. Background:…Does Fgatir Hypointensity Predict Outcomes After Deep Brain Stimulation For Action Tremors
Objective: To test whether efficacy of Deep Brain Stimulation (DBS) in different action tremor syndromes (Essential tremor, ET, ET-plus, or dystonic tremor as per IPMDS…Assessing Agreement of Self-Perception of Dysphagia in Individuals with Parkinson Disease and their Caregivers
Objective: To investigate the association of self-perception of dysphagia in individuals with Parkinson disease (IwPD) with their caregivers’ perceptions at early, mid and late stages…Tablet-Based Quantitative Evaluation of Finger Movement in Essential Tremor: A Visual-Motor Task Study
Objective: Extending our prior FMAS validation in Parkinson’s disease (PD), we utilized this tablet-based system to quantify finger movement profiles in Essential tremor (ET) patients…Correlational Study of the Clinical Impression of Severity Index for Parkinson’s Disease (CISI-PD) with Functional Mobility Measures
Objective: To evaluate the correlation between CISI-PD by examining its association with four widely-validated functional mobility measures in PD: the 5 Times Sit-to-Stand Test (5xSTS),…Rare Neurotoxicity of Cotrimoxazole A Movement Disorder Presentation In Elderly Patient
Objective: We report the case of an elderly woman with hyperkinetic movement disorders Background: Trimethoprim-sulfamethoxazole (TMP-SMX) is widely used for Pneumocystis jirovecii prophylaxis, but significant neurological toxicity…Chronic Vanadium Exposure Promotes Memory Impairment and Aggregation of Alpha-Synuclein, Tau and Amyloid Beta in Mouse Brain
Objective: In this study, we hypothesized that prolonged vanadium exposure may be a potential risk factor for Alzheimer's and Parkinson's diseases. Background: The interaction between…
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