Central cholinergic activity and risk of falls in patients with Parkinson’s disease and freezing of gait
Objective: We evaluated whether changes in cholinergic function might be related to increased fall risk in PD patients with Freezing of Gait (FoG). Background: FoG…Ginsenoside Rb1 Prevents MPTP-Induced Changes in Hippocampal Memory via Regulation of the α-Synuclein/PSD-95 Pathway
Objective: To explore the effects of ginsenoside Rb1 on the cognitive impairment of Parkinson’s disease (PD) model. Background: Memory deficiency is a common non-motor symptom…Exploring the cognitive workload during a visual search task in Parkinson’s disease
Objective: To investigate cognitive workload during a visual search task in patients with Parkinson's Disease (PD) Background: Visual search is one of the most important…Examining supplementary motor area-primary motor cortex connectivity in tremor-dominant Parkinson’s disease using a novel transcranial magnetic stimulation protocol to inform clinical practice
Objective: Objectives: (1) Measure test re-test reliability of dual-coil transcranial magnetic stimulation (TMS) measures of supplementary motor area-primary motor cortex connectivity (SMA-M1 connectivity). (2) Investigate…QPS over the supplementary motor area induced cortical excitability changes in human primary motor cortex: Comparison with Placebo effect
Objective: To explore the effects of quadripulse stimulation (QPS) over the supplementary motor area (SMA) in the healthy humans. Background: Repetitive transcranial magnetic stimulation (rTMS)…Motor learning and long duration response to levodopa in Parkinson’s disease.
Objective: To define the role of long-duration response (LDR) in motor learning, evaluating neurophysiological parameters in patients affected by Parkinson’s disease (PD) with and without…Unilateral increase of blink reflex recovery cycle in drug-naive hemiparkinson syndrome.
Objective: We assessed R2 Blink Reflex Recovery Cycle (R2 BRRC) in drug-naive Parkinson’s disease (PD) patients with unilateral tremor and/or rigidity, diagnosed as hemiparkinson syndrome,…Spatial distribution of functional clusters coding for reward and movement information in the striatal direct and indirect pathways
Objective: To obtain the insight how striatum processes reward based learning and motor information, we explored the responses of D1 and D2 medium spiny neurons…No evidence for early emotional processing in the subthalamic nucleus – a single neuron study
Objective: To provide evidence of early emotional processing at the single-neuron level in the STN. Background: A fast response to coarse threat signals in the…Abnormal frontal theta and beta oscillations during gait observation in Parkinson’s disease
Objective: To characterize the frontal oscillations during gait observation in Parkinson’s disease (PD) patients with (freezers) and without (non-freezers) freezing of gait. Background: Freezing of…
