Effects of mannitol treatment in a mice model of multiple system atrophy (MSA)
Objective: The aim of this study was to examine the effect of mannitol treatment in a mice model of MSA. Background: Alpha-synuclein aggregation represents the…Midbrain/pons area ratio and clinical features predict the prognosis of PSP
Objective: This study aims to characterize the natural history of PSP and to find predictors of shorter survival and early institutionalization including neuroimaging biomarkers. Background:…Analysis of Tau Burden and Distribution on the Spectrum of PSP Subtypes
Objective: The aim of this study was to assess the previous hypothesis about relationship between clinical spectrum of Progressive Supranuclear Palsy (PSP) and tau burden…Amyotrophic Lateral Sclerosis-Progressive Supranuclear Palsy Phenotype with Negative C9ORF72 Mutation
Objective: We report a rare case of amyotrophic lateral sclerosis (ALS) / progressive supranuclear palsy (PSP) phenotype. Background: Increasing evidence supports a common pathophysiology between…Evolution of diagnostic certainty and PSP-predominance types in 187 pathologically confirmed PSP patients
Objective: To examine the evolution of diagnostic certainty and clinical predominance types as defined by the movement disorder society (MDS) criteria for the clinical diagnosis…Referral and diagnostic time intervals from symptom onset to death in progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and Parkinson’s disease (PD)
Objective: To compare referral and diagnostic time intervals from index symptom to death in PSP/CBD and age-sex matched PD. Background: Misdiagnosis and delayed diagnosis are…Unusual prolonged survival in multiple system atrophy: A case report
Objective: To present a case of a patient with multiple system atrophy (MSA) parkinsonian subtype (MSA-P) with unusual long disease duration. Background: MSA is a…Utility of Acute Levodopa Challenge Test In Early Parkinsonism
Objective: This prospective cohort study was conducted to evaluate the sensitivity and specificity of different outcomes of acute levodopa challenge test(ALCT) (motor improvement, development of…Serum cholesterol level is associated with risk of MSA
Objective: We aim to ascertain the association between serum cholesterol and multiple system atrophy (MSA). Background: MSA, a common form of atypical parkinsonism, is a…Rapamycin for treating MSA: A preclinical proof of concept study
Objective: To assess the effects of rapamycin on motor behavior, α-synuclein burden and surrogate markers of neurodegeneration in a transgenic mouse model of multiple system…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.