Higher Levels of Serum Uric Acid Associated with Motor & Non-Motor Symptoms in Early Parkinson’s Disease
Objective: Uric acid (UA) has been shown to be potentially neuroprotective in Parkinson's disease (PD), a progressive neurodegenerative disorder that is clinically characterised by motor…MicroRNAs as Biomarkers for Parkinson’s Disease
Objective: To identify potential biomarkers for Parkinson’s disease by evaluating miRNA in cerebrospinal fluid samples collected from PD and healthy control subjects. Background: The diagnosis…Gender effects on clinical features in LRRK2 G2385R carriers and non-carriers in Parkinson’s disease
Objective: This study was to explore gender effects within the same genetic subtype and role of leucine-rich repeat kinase 2 (LRRK2) G2385R variants within the…Association of GBA polymorphisms and mutations with dementia in Parkinson disease: A 7-year study of three population-based incident cohorts
Objective: To study the effect of GBA variants on dementia in three deeply phenotyped population-based prospective cohorts of patients with incident Parkinson disease. Background: Dementia…Genome-wide association studies of motor and cognitive progression in Parkinson’s disease
Objective: Motor and cognitive progression in Parkinson’s is heterogeneous. Our aim is to identify single nucleotide polymorphisms (SNPs) associated with disease progression. Background: Rare genetic…eEF1A2 and Prdx1 as possible new targets for Parkinson’s disease therapeutics
Objective: We investigated expression of eEF1A2 and Prdx1 in differentiated SH-SY5Y cells in searching for possible new targets for Parkinson’s disease treatment. Background: Parkinson’s disease…Diagnostic utility of a targeted resequencing technique of next generation sequencing in detecting copy number changes in PARK2
Objective: We investigate feasibility of Next Generation Sequencing (NGS) targeted sequencing technique using Ampliseq® technology by Ion PGM® to detect copy number variation mutation in…Analysis of gene polymorphisms of Parkinson’s disease in Han Chinese population
Objective: Sequencing of Parkinson Disease（PD) genes were used in our research in order to study the polymorphism of PD related genes of Chinese Han people.…The Parkinson’s Families Project: A family-based study of early onset and familial Parkinson’s disease
Objective: The aim of this study is to identify new genetic variants that cause or predispose to Parkinson’s disease (PD). Our secondary aim is to…LRRK2 p.Leu119Pro and p.Leu488Pro in a family with neuropathologycally confirmed Parkinson´s disease without Lewy bodies
Objective: To describe the clinical features, genetic analysis and brain pathology of some members of a family affected by Parkinson´s disease. Background: Mutations of the…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.