Risk of developing the Parkinson’s disease against the background of diabetes mellitus type 2.
Objective: To evaluate whether type 2 diabetes at baseline is a risk factor for Parkinson's disease. Background: Parkinson’s disease is a chronic disorder in which…Functional Capacity in patients with Parkinson’s Disease are related to advanced glycation end-products
Objective: This study aimed to estimate the AGE consumption and formation in individuals with Parkinson's disease and to relate them with their functional capacity. Background:…Movement and symptom-modulated local field potentials in globus pallidus internus of Parkinson’s disease
Objective: To examine the relationship between local field potential (LFP) activity recorded from directional deep brain stimulation (DBS) leads in the internal segment of the…A videographic tool for quantitative assessment of the Glabellar Reflex
Objective: We developed a videographic tool to quantitatively assess the Glabellar Reflex (GR) in healthy patients for further analysis in Parkinson (PD) patients. Background: The…The contribution of striatal dopamine to feedforward motor control during gait initiation in Parkinson’s disease
Objective: To establish the contribution of striatal dopamine to gait initiation in Parkinson’s disease. Background: Gait initiation (GI) is characterized by anticipatory postural adjustments (APAs),…Dysbiosis of Gut Microbiota in a selected population of Italian Parkinson’s Disease patients
Objective: Our main objective was to investigate dysbiosis of gut microbiota in a selected population of Parkinson’s disease (PD) patients from center-south of Italy, examining…Tissue Engineered Nigrostriatal Pathway as an Anatomically-Inspired Test-Bed for Evaluating Axonal Pathophysiology
Objective: We previously developed the first micro-tissue engineered nigrostriatal pathway encased in a tubular hydrogel with 3D structure, multicellular composition, and architecture of long axonal…Parkinsonism alters directed connectivity in the cortico-subthalamo-pallidal circuit
Objective: To characterize how parkinsonism alters directed connectivity across the motor cortex (M1), subthalamic nucleus (STN), and internal segment of the globus pallidus (GPi). Background:…DNAJC13 in Parkinson’s disease; characterization of the p.N855S knock-in mouse model
Objective: To study the effects of DNAJC13 p.Asn855Ser mutant gene dysfunction in a physiological context, and to help define molecular mechanisms for disease, using a…Therapeutic intervention of LRRK2 kinase inhibitors in Vps35 p.D620N Parkinsonism
Objective: To explore the therapeutic potential of LRRK2 kinase inhibitors in a Vps35 p.D620N mouse model of Parkinsonsim. Background: The discovery of a missense mutation, Vps35 p.D620N…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.