Motivational effects on action selection and memory
Objective: Eye movements provide important insights into the pathophysiology of neurological disorders. Here two paradigms were devised to quantify effects of motivation on motor control…Levodopa-induced dyskinesia in Parkinson’s disease: Sleep matters
Objective: To investigate the relationship between slow wave activity (SWA) of non-rapid eye movement (NREM) sleep, which underlies adjustment of cortical excitability, and levodopa-induced dyskinesias…Influence of dopamine deficiency on interhemispheric crosstalk in Parkinson’s disease
Objective: To identify the significance of dopaminergic depletion in Parkinson’s disease (PD) on interhemispheric crosstalk using a complex bimanual tapping task. Background: Dopamine deficiency in…Profiles of microRNA in cerebrospinal fluid could be potential biomarkers for identifying motor subtype of Parkinson’s disease
Objective: We investigated CSF miRNA expression in PD and control subjects. We also evaluated if specific miRNA were differently expressed according to motor subtype of…Presence of Lewy dots in the brain of patients with Creutzfeldt-Jakob disease
Objective: We have investigated whether alpha-synuclein deposits exists in the brain of patients with Creutzfelt-Jakob disease Background: Creutzfeldt-Jakob’s disease (CJD) is a prion neurodegenerative disorder…No MPTP-induced behavioral deficits or Striatal field potential alterations in crossbreds of MPTP-susceptible and MPTP-resistant mice strains
Objective: To evaluate the electrophysiological and motor behavioural correlates of strain-dependent differential susceptibility of mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and the role of admixing thereon. Background:…Frontal-subcortical cognitive impairments in Parkinson’s patients with freezing of gait
Objective: To evaluate the relationship between frontal-subcortical cognitive dysfunctions and freezing of gait (FOG) in Parkinson's disease (PD). Background: FOG is a complex and multisystem…Molecular Genetics and Functional Studies of LRRK2 Gene Variations in Parkinson’s Disease
Objective: To evaluate the function role of ROC domain in the brains of LRRK2 transgenic mice model and normal control mice. Background: Mutations in leucine-rich…Role of microglia in the transmission of α-syn-containing exosomes
Objective: we investigated the role of microglia in the transmission of α-syn-containing exosomes and offer a new insight into the mechanism of PD pathogenesis. Background:…The difference in posture reaction against backward perturbation between patients with Parkinson’s disease and healthy controls
Objective: To investigate the posture reaction in patients with Parkinson’s disease (PD) and healthy age-matched controls when they were given quantitative backward perturbation. Background: Although…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.