Efficacy of opicapone in Parkinson’s disease patients with ‘early’ motor fluctuations: The BIPARK-I double-blind experience
Objective: To evaluate the efficacy of opicapone (OPC) in levodopa-treated Parkinson’s Disease (PD) patients with ‘early’ motor fluctuations. Background: OPC, a novel once-daily COMT inhibitor,…Can choice of games influence the therapeutic results obtained by training in virtual reality for gait improvement in people with Parkinson’s disease?
Objective: The aim of this study was to compare the efficiency of two different combination of games to improve the gait performance in PPD. Background:…Efficacy of sublingual apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: Results from the Phase 3 double-blind, placebo-controlled trial
Objective: To evaluate the efficacy of APL-130277 (APL) in a double-blind, placebo-controlled trial. Background: OFF episodes are a common, disabling complication of Parkinson’s disease (PD)…Effect of mindfulness yoga on psychological distress in people with Parkinson’s disease (PD): A randomized controlled trial
Objective: To determine the effects of yoga versus conventional stretching and resistance training exercises (SRTE) on psychological, physical, spiritual, and health-related quality-of-life (HRQOL) outcomes among…Yerba Mate (Ilex paraguaiensis) protects dopaminergic neurons degeneration and improve their maturation in culture
Objective: To evaluate the effect of Mate leaves extracts on the survival and maturation of dopaminergic neurons in vitro. Background: Parkinson's disease (PD) is caused…Long-Duration Response to Levodopa in advanced Parkinson’s Disease: Relevance for RCT on Disease-Modifying therapies
Objective: (1) To investigate the natural history of Parkinson’s disease (PD) in a cohort of newly diagnosed patients and (2) the response to acute levodopa…The anti-dyskinetic effect of the clinically-available 5-HT3 receptor antagonist granisetron in the 6-OHDA-lesioned rat model of Parkinson’s disease
Objective: To determine the effect of the serotonin 3 (5-HT3) receptor antagonist granisetron, a clinically-available anti-emetic, on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia. Background: Dopamine replacement with L-DOPA…Exploring the utility of the ChulaPD intelligent Parkinson’s disease car to determine naturalistic driving ability in Parkinson’s disease patients: A pilot study of 10 patients
Objective: To examine the naturalistic driving performance in PD patients compared to controls and to determine if the PD patients showed diminished abilities. Background: Competence…Gastric Retention of the Accordion Pill™: Results From MRI Studies With Parkinson’s Disease Patients and Healthy Volunteers
Objective: To determine gastric retention (GR) of the Accordion Pill™ (AP) in patients with Parkinson’s disease (PD) and healthy volunteers. Background: While carbidopa/levodopa (CD/LD) is…Compensation strategies for gait impairments in Parkinson’s disease
Objective: To provide an overview of available compensation strategies for gait impairments in Parkinson’s disease (PD) using an expert-opinion based methodology. Background: Patients with PD…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.