L-Dopa responsiveness in early Parkinson’s disease: Results from the United Kingdom Tracking Parkinson’s study
Objective: We wanted to evaluate L-dopa responsiveness in a large cohort of patients with recently diagnosed Parkinson’s disease (PD) using an acute L-dopa challenge test.…Efficacy of CVT-301 (levodopa inhalation powder) for treatment of OFF periods in Parkinson’s disease
Objective: Post-hoc analysis of subjects with Parkinson’s disease (PD) achieving > 30% reduction in UPDRS motor score (UPDRSIII) from pre- to post-dose over the first…Perceived Psychosocial Impacts of a Therapeutic Yoga Intervention for Individuals with Parkinson’s Disease (PD)
Objective: This qualitative study sought to understand the psychosocial impacts of a therapeutic yoga intervention for individuals with PD originally designed to improve balance and…Efficacy of combined treatment with acupunture and bee venom acupuncture for Parkinson’s disease: Double blind randomized controlled trial
Objective: The aim of this study was to evaluate the efficacy of acupuncture and BVA for IPD through a sham-controlled trial. We also investigated whether…Safety of sublingual apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: Results from a Phase 3 double-blind, placebo-controlled trial
Objective: To evaluate the safety of APL-130277 (APL) in the double-blind, placebo-controlled trial Titration Phase (TP) and Maintenance Phase (MP). Background: OFF episodes are a…A phase Ib trial studying the safety and tolerability of IRL790 in patients with Parkinson’s disease and levodopa-induced dyskinesia
Objective: The primary objective was to investigate the safety and tolerability of IRL790 in PD patients with LID in a randomized controlled trial. Background: IRL790…Safety and Efficacy of Levodopa-Carbidopa Monotherapy in Patients with Advanced Parkinson’s Disease
Objective: Evaluate efficacy/safety of levodopa-carbidopa intestinal gel (LCIG) daytime monotherapy (with/without nighttime oral carbidopa/levodopa) vs polytherapy (LCIG with >1 adjunctive therapy) in advanced Parkinson’s disease…Individualization of levodopa treatment using a microtablet dispenser and ambulatory accelerometry
Objective: This four-week open-label observational study describes the effect of introducing a microtablet dose dispenser and adjusting doses based on objective free-living motor symptom monitoring…Dual task in the daily life of patients with Parkinson’s disease
Objective: Determine which of the types of motor or cognitive tasks interfere most severely in the dual task in the daily life of patients with…The complementary relationship between zonisamide and istradefylline in treating patients with Parkinson’s disease
Objective: To investigate patients with Parkinson’s disease (PD) who received zonisamide and istradefylline at the same period. Background: Zonisamide and istradefylline are anti-PD drugs with…
