Effect of dopamine agonists versus levodopa as initial treatment in Parkinson’s Disease
Objective: We evaluated the efficacy of different starting drugs in the treatment of Parkinson's disease (PD), in order to further explore the initial therapy of…Effects of JN403, an α-7-nicotine-acetylcholine-receptor (α7-nAChR) agonist on human alpha-synuclein-mediated in vitro and in vivo models of Parkinson’s disease
Objective: To investigate whether JN403, a novel selective agonist of α-7-nicotine-acetylcholine-receptors (α7-nAChRs) can suppress inflammation and toxicity in human alpha-synuclein (αSyn) induced in vitro and…Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial
Objective: To investigate whether women and men with Parkinson's disease (PD) may differ in their biochemical and clinical responses to long-term treatment with urate-elevating inosine.…Treatment of Levodopa Dose Failure with Subcutaneous Apomorphine Injection
Objective: We evaluated a subset of patients who were enrolled in the AMIMPAKT trial of sc apomorphine injection to treat morning akinesia (see reference) who…Levodopa induced dyskinesia is preventable (15 years experience using continuous dopaminergic stimulation)
Objective: To evaluate whether levodopa induced dyskinesia is preventable in the treatment of patients with Parkinson’s disease. Background: Dyskinesia is one of the major complications…Characteristics of dopaminergic treatments in advanced Parkinson’s before levodopa-carbidopa intestinal gel infusion: Data from 107 tested patients
Objective: To describe the characteristics of dopaminergic treatments in a large group of patients with advanced Parkinson’s Disease (APD) in which current non-invasive therapy (oral,…Immediate Effect of Elastic Taping on Balance and Postural Control in Early Parkinson’s Disease: A Pilot Study
Objective: The purpose of this study is to investigate the immediate effect of elastic taping on balance and postural control in early Parkinson's disease. Background:…Activities of Daily Living and Quality of Life in Patients with Advanced Parkinson’s Disease Who Are Treated with or Planning to Use Device-Aided Treatments
Objective: To correlate activities of daily living (ADL) and quality of life (QoL) in advanced Parkinson’s disease (APD) patients with ongoing or planned device-aided treatment…STEEred vs RING-mode Deep Brain Stimulation for Parkinson’s disease: STEERING trial
Objective: To evaluate whether directional STN DBS is more effective than ring-mode DBS in reducing PD motor symptoms, and to investigate if directional STN DBS…A Double-Blind, Randomized, Placebo-Controlled, Cross-Over Phase IIa Trial to Evaluate the Efficacy of CVXL-0107 on Parkinson-Related Symptoms and Levodopa-Induced Dyskinesia in Advanced Parkinson’s Disease
Objective: To evaluate the efficacy of CVXL-0107 on motor symptoms and on levodopa-induced dyskinesia in advanced Parkinson’s disease (PD) patients. Background: CVXL-0107 is a glutamate…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.