Unusual eye movement found in antineuronal nuclear autoantibody type 2 (ANNA-2); both seesaw nystagmus and opsoclonus may provide a novel mechanism
Objective: We conceptualized a novel mechanism for seesaw nystagmus highlighting reverberations due to abnormal hyperexcitability of the reciprocally innervating circuit of excitatory burst neuron in…A Case of Secondary Myoclonic Hyperkinesia
Objective: Hyperkinesias are a type of movement disorders characterized by involuntary muscle movements. There are different variants of hyperkinesia, including tremor, chorea, myoclonic movements, etc.…Ocular motor function in stiff person syndrome – Role of GABA and beyond
Objective: Delineate pathophysiology of gaze-holding function in stiff person syndrome (SPS). Background: Glutamic acid decarboxylase (GAD) catalyzes conversion of glutamate to gamma-aminobutyric acid (GABA). Anti-GAD…Multimodal evoked potential analysis in Woodhouse-Sakati Syndrome
Objective: Investigate Woodhouse-Sakati syndrome through analysis of multimodal evoked potentials at various clinical stages, to assess their possible role as an aid in determining the…Primary familial brain calcification – The impact of calcifications on the development of motor symptoms
Objective: The aim of the present study was to investigate whether the nigro-striatal system in a genetic mouse model of primary familial brain calcification (PFBC)…Intranasal delivery of insulin for the restoration of memory signaling in Alzheimer disease
Objective: Objective of this study is to develop delivery-system to overcome BBB by employing novel, non-invasive approach via nasal route. Background: Alzheimer's disease(AD), a form…Movement Disorders Phenomenology in Focal Motor Seizures
Objective: To examine the extent to which focal motor seizures can present with a phenomenology fulfilling diagnostic criteria for one or more movement disorder. Background:…Relationship between CTG repeats, Muscle Weakness and Respiratory Dysfunction in Myotonic Dystrophy Type 1
Objective: This study aims to assess the association between CTG repeats, muscle weakness and respiratory dysfunction in a cohort of individuals with myotonic dystrophy type…Reduction of neuroinflammation by selective inhibition of the N-type calcium channel is beneficial in various animal models of neurodegeneration, here in the SOD1G93A transgenic mouse model of ALS
Objective: Neuroinflammation is a pathological hallmark of several neurodegenerative diseases. We speculated that reduction of calcium ion influx specifically in neurons should reduce inflammatory cellular…Eye Movement Abnormalities Correspond to Pontine Atrophy in Wilson Disease
Objective: This study aims to characterize eye movement (EM) abnormalities in Wilson´s disease (WD) and to assess their relation to clinical severity of WD and…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.