Istradefylline improves not only motor symptoms but also sleep disturbance, daytime sleepiness, and QOL of Parkinson’s disease patients.
Objective: This study analyzed the clinical effectiveness of istradefylline in terms of sleep disturbance in Parkinson’s disease (PD) patients. Background: A selective adenosine A2A receptor…Improving Racial and Ethnic Diversity in Parkinson`s Disease Clinical Trials
Objective: To identify and overcome challenges to recruiting minorities in Parkinson's Disease experimental therapeutic trials. Background: Inadequate representation of ethnic and minority population poses substantial…Deep brain stimulation in Parkinson’s disease: Outcome after more than nine years
Objective: The aim of this study is to examine the long-term effects of deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson’s disease…Alternations of Metabolic Profile and Kynurenine Metabolism in the Plasma of Parkinson’s Disease
Objective: The purpose of this study was to identify potential plasma metabolic biomarkers for Parkinson’s disease (PD) Background: PD, characterized by a slowness of movement…Observational study of the effectiveness and tolerability of rotigotine+levodopa therapy in older vs younger Parkinson’s disease patients
Objective: Prospective non-interventional study conducted in routine clinical practice (PD0013; NCT02227355) to compare effectiveness and tolerability of rotigotine+levodopa (RTG+Ldopa) in Parkinson’s disease (PD) patients aged…Factors associated with perceived walking difficulties in people with Parkinson’s disease
Objective: To investigate factors that independently contribute to perceived walking difficulties in people with Parkinson’s disease (PD). Background: Despite that walking difficulties are common in…Evaluation of rotigotine transdermal patch in combination with low or high dose levodopa in patients with Parkinson’s disease: post-hoc analysis
Objective: To investigate the value of adding the dopamine agonist (DA) rotigotine (RTG) to low (<400mg/day) or high (≥400mg/day) levodopa (Ldopa) doses in patients with…A prospective randomized cross-over study of telemedicine system in Parkinson’s disease
Objective: To investigate the validity of telemedicine system in Parkinson’s disease(PD). Background: PD patients may be difficult to visit the hospitals because of decline of…Baseline characteristics of the population enrolled to a randomized clinical study of subcutaneous levodopa/carbidopa (ND0612) infusion in patients with advanced PD
Objective: To evaluate whether continuous 24 hours delivery of subcutaneous ND0612 offers practical and clinical benefits over continuous delivery over the waking day (14 hours).…Virtual research visits in individuals with Parkinson disease enrolled in a clinical trial: REACT-PD Study Interim Analysis
Objective: To demonstrate the feasibility, reliability, and value of conducting web-based clinical trial assessments in individuals with Parkinson disease (PD). Background: Increasing interest has been…