Sentence comprehension in Slovak speaking patients with Parkinson´s disease – preliminary results
Objective: The aim of our research was to analyze comprehension of various syntactic constructions in Slovak-speaking PD-ND patients . We were particularly interested in exploring…Aquatic Physical Exercises: Balance in People with Parkinson’s Disease
Objective: to evaluate the repercussion of an aquatic physical exercise program on the body balance of people with Parkinson's disease (PD) in stages 2, 5…ND0701: A new concentrated formulation of Apomorphine for continuous subcutaneous administration – human PK data
Objective: To evaluate the PK and relative bioavailability of ND0701, a subcutaneously (SC) infused apomorphine-base product candidate, and a commercial apomorphine-HCl product. The secondary objective…Spinal cord stimulation as therapeutic option in gait disorder in Parkinson disease.
Objective: We aim to study the effect of spinal cord stimulation over gait in parkinson disease without pain nor neuropathy. Background: Axial symptoms in the course…Identification of the optimal carbidopa concentration in subcutaneously administered ND0612
Objective: To identify the concentration of subcutaneous (SC) carbidopa (CD) that provides optimal bioavailability of a concomitant fixed concentration of levodopa (LD) when administered via…Focused ultrasound subthalamotomy for Parkinson’s disease: A pilot study
Objective: To evaluate feasibility, safety and effectiveness of unilateral subthalamotomy performed with MRIgHIFU to treat the cardinal motor features of PD Background: Ablative functional neurosurgery for…Sample size estimation for clinical trials in de novo Parkinson’s disease (PD): Results from the Parkinson’s Progression Markers Initiative (PPMI) Study
Objective: To use clinical and biological data from PPMI to estimate sample size for disease modification studies in de novo PD Background: One barrier to…Caffeine as a Treatment for Parkinson’s Disease: A Randomized Controlled Trial (CafePD)
Objective: To assess the effects of caffeine on patients with Parkinson's disease. Background: Multiple studies have linked use of caffeine, an adenosine antagonist, to a…Multi-modal retention in a phase III clinical trial in early Parkinson disease (STEADY-PD III)
Objective: To evaluate novel retention strategies in an ongoing phase 3 clinical trial in individuals with Parkinson disease (PD) Background: Adequate participant retention is a…Exergaming in Patients with Parkinson’s Disease
Objective: To analyze the effects of exergaming on functional balance and fatigue in patients with Parkinson's disease Background: Interventions that promote the integration of multi-sensory,…