MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2017 International Congress

    Olfactory Impairment in Parkinson’s Disease and White Matter Abnormalities in Central Olfactory Areas

    S. Sobhani, M. Aarabi (Tehran, Islamic Republic of Iran)

    Objective: To determine white matter abnormalities in PD patients with various degrees of olfactory impairment. Background: Neuroimaging results of PD brain based on diffusion tensor…
  • 2017 International Congress

    The influence of LRRK2 mutations on cholinergic system in manifest and prodromal stage of Parkinson’s disease: a positron emission tomography study

    S. [email protected], D. Wile, J. Fu, J. Valerio, E. Shahinfard, S. McCormick, R. Mabrouk, N. Vafai, J. McKenzie, N. Neilson, A. Perez-Soriano, J. Arena, M. Cherkasova, J. Zhang, C. Zabetian, J. Aasly, Z. Wszolek, M. McKeown, V. Sossi, A. Stoessl (Beijing, China)

    Objective: To evaluate the effects of leucine-rich repeat kinase 2 (LRRK2) mutations on the central cholinergic system in both manifesting and non-manifesting carriers using PET…
  • 2017 International Congress

    Functional MAOB gene intron 13 polymorphism predicts putaminal dopamine turnover in de novo Parkinson’s disease

    M. Löhle, G. Mangone, M. Wolz, B. Beuthien-Baumann, L. Oehme, J. Hoff, J. Kotzerke, H. Reichmann, J.-C. Corvol, A. Storch (Rostock, Germany)

    Objective: To examine the effects of common functional polymorphisms in genes involved in dopamine metabolism on striatal dopamine turnover estimated as the inverse of the…
  • 2017 International Congress

    Substantia nigra area evaluated by neuromelanin-sensitive MRI as an imaging biomarker of disease progression in Parkinson’s disease

    M. Fabbri, S. Reimão, M. Carbalho, R. Nunes, D. Abreu, L. Guedes, R. Bouça, P. Lobo, C. Godinho, M. Coelho, N. Gonçalves, M. Rosa, A. Antonini, J. Ferreira (Lisbon, Portugal)

    Objective: to investigate the pattern of substantia nigra - neuromelanin (SN-NM) area loss and contrast ratio (CR) intensity changes in late-stage Parkinson’s disease (LSPD) patients,…
  • 2017 International Congress

    Alterations in Dynamic Brain Connectivity Patterns in Parkinson’s Disease

    X. Dan, A. Liu, J. Wang, M. McKeown, T. Wu, P. Chan (Beijing, China)

    Objective: To explore the time varying brain connectivity networks in Parkinson's disease (PD) during resting-state fMRI and to investigate the correlate between connectivity dynamics and…
  • 2017 International Congress

    Hippocampal iron deposition in Parkinson disease and Parkinson disease with dementia/Lewy body dementia: quantitative susceptibility mapping assessments

    M. Miyata, S. Kakeda, J. Moriya, H. Narimatsu, T. Sato, H. Adachi, Y. Wang, Y. Korogi (Kitakyushu, Japan)

    Objective: We compared quantitative susceptibility mapping (QSM) values in the hippocampi among patients with Parkinson disease (PD) and PD with dementia (PDD)/ Lewy body dementia…
  • 2017 International Congress

    The prevalence of cerebral microbleeds in patients with Parkinson’s disease and multiple system atrophy

    J.-M. Kim (Seongnam, Republic of Korea)

    Objective: Here, we compared the prevalence of cerebral microbleeds (CMBs) in patients with parkinsonian disorders, including Parkinson’s diseaseParkinson’s disease (PD) and multiple system atrophy (MSA).…
  • 2017 International Congress

    Parkinson’s disease with visual hallucination: optic radiation abnormalities on phase difference-enhanced imaging (PADRE)

    M. Miyata, S. Kakeda, T. Yoneda, H. Narimatsu, T. Sato, K. Okada, H. Adachi, Y. Korogi (Kitakyushu, Japan)

    Objective: We assessed structural abnormalities of optic radiation (OR) in patients with Parkinson disease (PD) with dementia (PDD) and dementia with lewy bodies (DLB) by…
  • 2017 International Congress

    Hypertension and Parkinson’s disease

    B. Giordano, G. Pagano, J. Hood, N. Ferrara, M. Politis (London, United Kingdom)

    Objective: To compared clinical burden, neuropsychological features, CSF and imaging pathology in early untreated PD patients with and without HT. Background: Hypertension (HT) has been…
  • 2017 International Congress

    The role of phosphodiesterase 4 in sleep disturbances in Parkinson’s disease

    H. Wilson, G. Pagano, F. Niccolini, N. Muhlert, C. Coello, M. Mehta, G. Searle, R. Gunn, E. Rabiner, T. Foltynie, M. Politis (London, United Kingdom)

    Objective: We aimed to assess the association between phosphodiesterase 4 (PDE4) expression and sleep disturbances in vivo using combined multimodal magnetic resonance imaging (MRI) and…
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