The score changes of clinical symptom assessment scales for multiple system atrophy in 2-3 years
Objective: To examine the extent of disease progression for multiple system atrophy (MSA) during relatively long duration. Background: The knowledge of MSA natural history is…Heart rate variability and sympathetic skin response are useful in the evaluation of Parkinson’s disease, AMS, and Parkinson plus syndrome, but underutilized in daily clinical practice
Objective: Assess the heart rate (HR) coefficient of variance (CV) in three conditions: supine, active standing and during deep breathing; and measure the sympathetic skin…A longitudinal observational study of a cohort of patients with PSP/CBD: The JALPAC project
Objective: To identify PSP/CBD progression biomarkers both to improve understanding of disease etiology and course, and to provide crucial tools to enhance the likelihood of…Could tonic chin electromyogram density be a potential marker for differentiating atypical Parkinsonian syndromes from Parkinson’s disease among alpha-synucleinopathies?
Objective: The study aimed to examine whether the video-polysomnography (vPSG) could provide some clues for differentiating atypical Parkinsonian syndromes (APS) from Parkinson's disease (PD) among…Apraxia of speech as the initial manifestation of progressive supranuclear palsy
Objective: We report a patient with apraxia of speech as the initial symptom who finally developed a progressive supranuclear palsy. Background: Progressive supranuclear palsy (PSP)…High frequency of mutations in the glucocerebrosidase (GBA) gene among Ashkenazi Jews with dementia with Lewy bodies
Objective: The objective of this study was to characterize, clinically and genetically, anAshkenazi Jewish cohort of patients diagnosed with DLB, looking for the association with…Early stridor onset predicts survival in multiple system atrophy
Objective: To evaluate the predictive value of stridor and of its latency of onset in a cohort of Multiple System Atrophy (MSA) patients referred to…Quantitative MRI measurement of regional cerebellar involvement in patients with progressive supranuclear palsy
Objective: We aimed to evaluate cerebellar involvement in PSP using MRI segmental volumetric analysis. Background: Progressive supranuclear palsy (PSP) is characterized clinically as postural instability…Atypical parkinsonism in C9orf72 expansions: A case report and systematic review of 45 cases from the literature
Objective: To provide a systematic clinical characterisation of C9orf72-associated parkinsonism. Background: While C9orf72 repeat expansions usually present with frontotemporal dementia (FTD) and/or amyotrophic lateral sclerosis…Transient mild hyperglycemia as diagnostic tool for idiopatic Parkinson’s disease triggered by psychoemotional stress
Objective: We studied clinical features and the levels of glucose in blood of patients with idiopathic PD (IPD) of different sages and duration who had…