A case series of sigmoid volvulus in Parkinson’s disease
Objective: To study the outcomes of patients with Parkinson's disease (PD) who were admitted with a diagnosis of sigmoid volvulus. Background: Constipation is a common…Inhibition of nociceptive responses by modulating serotonergic signals at the rostral ventromedial medulla in 6-OHDA-induced Parkinson’s disease rat model
Objective: We aimed to determine whether the descending 5-HT facilitatory pathway from rostral ventromedial medulla (RVM) and the extracellular 5-HT in RVM are involved in…Orthostatic intolerance and falls in Parkinson’s disease
Objective: Primary objective: to assess the relationship between falls, orthostatic intolerance and orthostatic hypotension (OH) in patients with Parkinson's disease (PD). Secondary objective: to assess…Impaired hippocampal neurogenesis associates with serotonergic axonal degeneration in transgenic rat and mouse models of Parkinson’s disease
Objective: To evaluate the impact of α-synuclein accumulation on the hippocampal serotonergic system and hippocampal plasticity in two different α-synuclein expressing rodent models. Background: Parkinson's…Awareness and perception of gastrointestinal symptoms in Parkinson´s disease: A survey of patients and caregiving relatives
Objective: The purpose of this survey was to determine the awareness and perception of gastrointestinal (GI) symptoms in patients and caregiving relatives (for simplicity hereunder…Assessment of gait dysfunction in patients with Parkinson’s disease and REM behavioral disorder
Objective: To determine if Parkinson's disease patients with REM behavioral disorder (RBD) have worse gait abnormalities and freezing of gait when compared to those without…Unawareness of causes of sudden deterioration in Parkinson’s patients in movement disorder clinic
Objective: To evaluate patient's awareness of reversible causes of worsening of Parkinson's disease (PD)1, their impact on symptoms and the role of abdominal x-ray (PFA)…Motor rigidity selectively associates with impaired odor identification in Parkinson’s disease
Objective: To investigate the relationship between impairments of the cardinal motor symptoms and odor identification deficits in Parkinson's disease (PD). Background: Although hyposmia has been…Dementia in Parkinson’s disease is associated with increased diffusivity in amygdala and external capsule
Objective: To identify which regions are associated with dementia in Parkinson's disease (PD) brains. Background: Dementia is common in advanced PD and its early development…Lack of association between LRRK2 G2385R and cognitive dysfunction in Korean patients with idiopathic Parkinson’s disease
Objective: We investigated whether the G2385R polymorphism in LRRK2, a risk allele for the development of idiopathic Parkinson's disease (IPD) in East Asians, is associated…