Clusterin CSF levels in differential diagnosis of neurodegenerative disorders
Objective: To find a specific in vivo marker to improve a differential diagnosis between Parkinson´s disease and atypical Parkinsonian syndromes, especially early in the course…LRRK2, MAPT and HTRA2 mutations in the pedigree of familial neurodegenerative parkinsonism with cognitive deterioration spanning five generations in a genetically isolated population of south-eastern Moravia, Czech Republic
Objective: To obtain genetic information about the individuals with confirmed parkinsonism in an isolated rural region in south-eastern Moravia, Czech Republic. Background: An epidemiological study…Unusual phenotype of pathologically confirmed progressive supranuclear palsy with autonomic dysfunction and cerebellar ataxia
Objective: To report two cases of patients with unusual manifestation of pathologically confirmed PSP. Background: Based on the results of recent multicenter clinical-pathological studies, it…Serum brain-derived neurotrophic factor as an indication of disease state in parkinsonism and RBD
Objective: Evaluation of peripheral concentrations of brain-derived neurotrophic Factor (BDNF) in patients with Parkinsonian disorders and correlation with clinical measurements of disease progression to elucidate…Loss of FBXO7 (PARK15) leads to disturbances in proteasomal function and models parkinsonism-like and pyramidal symptoms in mice
Objective: To model Parkinsonian-pyramidal syndrome (PARK15) in mice and investigate the impact of loss of F-box only protein 7 (FBXO7) in neurons on proteasomal activity.…PSP and HIV: Causality or coincidence?
Objective: Our aim was to describe the clinical picture of an HIV patient with a progressive neurodegenerative disorder likely Progressive supranuclear palsy (PSP). Background: Movement…Generation and characterization of iPSC-derived nigral dopaminergic and pyramidal glutamatergic neurons from patients affected by multiple system atrophy
Objective: The aim of the present study is to generate dopaminergic and pyramidal neurons from iPSCs of MSA patients in order to establish an in…Cognitive impairment in patients with progressive supranuclear palsy and multiple system atrophy
Objective: Assessment, description and mutual comparison of cognitive impairment in patients with progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). Background: In most recent…Zolpidem ameliorates the freezing of gait in a patient with PAGF (pure akinesia with freezing of gait)-the possible neural mechanism
Objective: To investigate the possible mechanism of amelioration of freezing of gait (FOG) in a patient with PAGF (Pure Akinesia with Freezing of Gait) by…Composite autonomic symptom scale-31 (COMPASS-31) is useful for evaluation of autonomic dysfunction in patients with parkinsonism
Objective: To investigate the usefulness of composite autonomic symptom scale 31 (COMPASS-31) in patients with parkinsonism by comparing COMPASS-31 between PD and MSA patients, and…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.