Stage dependent alteration of cortical excitability in patients with hepatic encephalopathy
Objective: To evaluate cortical excitability in patients with hepatic encephalopathy (HE) using transcranial magnetic stimulation (TMS). Background: HE is a neuropsychiatric disorder manifesting with movement…The regulation of ASIC1a on dopamine release and its implication in the pathogenesis of Parkinson’s disease
Objective: To study the distribution of acid-sensing ion channel 1a (ASIC1a) in dopaminergic neurons and its role in regulating dopamine release, and to explore its…Single unit activity of medial thalamus during goal-directed motor and cognitive behavior in patients with cervical dystonia
Objective: To 1) study neuronal activity of medial thalamic nuclei (MD, CM-Pf) and its role in cognitive and motor human activity and 2) evaluate neuronal…Inferring the causal interplay of motor related brain areas in the aging brain: A dynamic causal modeling (DCM) approach
Objective: To investigate the causal interplay of brain areas during the performance of a complex bimanual motor task in young and elderly subjects. Background: Coordination…TMS-EEG markers of inhibitory deficits in Huntington’s disease
Objective: Given the GABAergic nature of TMS-evoked EEG activity, we tested whether GABAergic deficits in Huntington's disease (HD) patients produce any significant change in TMS-EEG…Automatic event-detection for the neurophysiological evaluation of voluntary and involuntary movements
Objective: This project aims at creating a tool for automatic EMG event- detection to support clinicians in this process. Background: Neurophysiological evaluation of voluntary and…Motor cortex neuroplasticity and learning following high-intensity interval exercise
Objective: To determine the effect of high-intensity interval (HIT) exercise on motor cortex plasticity and learning in healthy young adults. Background: Motor skill learning requires…Mirror movements in Moebius syndrome: Mirroring beyond movements
Objective: To understand pathophysiology of mirror movements (MM) in Moebius syndrome patients by performing comprehensive neurophysiologic studies in two patients. Background: MM are involuntary movements…Selective activation of excitatory cell groups in the medial medulla differentially affects spatial-temporal gait parameters
Objective: To study the role of excitatory neurons in the ventromedial medulla in gait using Designer Receptors Exclusively Activated by Designer Drugs. Background: The medial…Refined basal ganglia model accounting for GPi modulation of thalamic tonic and burst modes
Objective: To test our hypothesis that a principal role of GPi GABAergic output is to regulate the dual burst and tonic modes of thalamocortical neurons.…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.