DaTscan in clinical evaluation of Multiple System Atrophy
Objective: To explore accuracy of DaTscanTM Ioflupane I123 Injection (DaTscan) in a multiple system atrophy (MSA) cohort Background: There are isolated cases of normal DaTscan in neuropathologically confirmed MSA-cerebellar subtype (MSA-C)…Unusual MRI findings of the syndrome of acute bilateral basal ganglia lesions in diabetic uremia with hyperglycemia associated dyskinesia
Objective: To describe the unusual image findings and clinical manifestations of the syndrome of acute bilateral basal ganglia lesions in a diabetic uremic patient with…Striatal dopamine transporter abnormalities in pure autonomic failure and speculation about the relationship with Lewy bodies
Objective: To reveal dopamine transporter (DAT) abnormalities in pure autonomic failure (PAF) and speculate about the relationship with the Lewy body progression pathway. Background:…Holmes’ tremor and olivary hypertrophy: lessons from this neuroanatomical correlation
Objective: To describe the neuroanatomical correlations of unilateral versus bilateral hypertrophic olivary degeneration (HOD) in three patients diagnosed with Holmes’ (rubral) tremor, secondary to midbrain…Loss of PDE10A expression in patients with PDE10A and ADYC5 mutations
Objective: To assess phosphodiesterase 10A (PDE10A) expression in vivo, using [11C]IMA107 PET in patients with PDE10A and adenylate cyclase 5 (ADYC5) mutations. Background: Cyclic adenosine…Identification of a trehalose treatment regimen with potential to be translated into a therapeutic for the treatment of Parkinson’s disease
Objective: To evaluate the preclinical efficacy of trehalose and to identify a dosing regimen that can be used to clinically evaluate trehalose as a disease-modifying therapy…The efficacy of continuous apomorphine infusion in advanced PD patients with cognitive impairments
Objective: To review the outcome of continuous apomorphine infusion (CAI) in advanced Parkinson’s disease (PD) patients at the rehabilitation unit of the Parkinson Expertise Center…Neuroticism and depression is associated with impulse control disorder in Parkinson’s disease: a controlled study
Objective: Cross-sectional assessment of personality trait, impulsivity, depression and anxiety collected prospectively in Parkinson’s disease (PD) with impulse control disorders (PD-ICD) compared to a matched…Using cognitive computing to identify compounds with antidyskinetic potential for Parkinson’s disease
Objective: IBM Watson for Drug Discovery (WDD) is a platform that analyzes vast quantities of scientific data to help researchers identify hidden connections and formulate…Onabotulinumtoxin A (Botox) displays superior activity to incobotulinumtoxinA (Xeomin) in multiple in vitro and in vivo assays
Objective: This study was conducted to assess in vivo and in vitro activity of 50 U, 100 U, and 200 U vials of incobotulinumtoxinA (Merz,…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.