Multimodal biomarkers as predictors of cognitive decline in Parkinson’s Disease
Objective: To identify a set of multimodal biomarkers to predict cognitive decline in non-demented Parkinson’s disease patients. Background: People with Parkinson’s Disease are at high…Prospective longitudinal CSF measurements and cognitive decline in GBA-associated Parkinsonism: not Abeta or Tau but Lewy body pathology?
Objective: To evaluate whether concomitant Ab and Tau pathology might contribute to the prominent cognitive decline in PD_GBA. Background: A considerable proportion of idiopathic Parkinson’s…Predict cognitive decline with non-clinical markers in Parkinson’s disease
Objective: In this study, we investigated whether [123I]FP-CIT single photon emission computed tomography (SPECT) imaging measures and CSF marker profiles predict CI in PD patients…Genetic variations in Amyloid-beta1-42 clearance proteins determine onset of dementia in Parkinson’s disease and dementia with Lewy bodies
Objective: To evaluate whether genetic variants in genes known to be associated with Abeta1-42 clearance contribute to the interval between ages at onset of parkinsonism…Sleep architecture in Parkinson´s disease and Parkinson’s disease associated dementia
Objective: To evaluate the differences in early sleep architecture between patients with Parkinson’s disease (PD) and Parkinson’s disease associated dementia (PDD). Background: Disorders of sleep…The value of classical cerebrospinal fluid protein ratios and peripheral inflammation in Parkinson’s disease cognitive impairment
Objective: To evaluate cerebrospinal fluid (CSF) levels of proteins associated with neuropathological inclusions and their ratios, and CSF and plasma levels of inflammatory proteins as…Quantifying reinforcement learning deficits in early stage Parkinson’s patients using a strategic decision-making task
Objective: 1.Characterize deficits in reinforcement learning processes in PD during a strategic game analogous to Rock-Paper-Scissors (RPS). 2.Examine the effects of dopaminergic (DA) treatment on…Domain-specific impact of cerebral white matter hyperintensities on Parkinson’s disease cognitive functioning
Objective: In this study, we investigate the relationship between white matter hyperintensities (WMH) and Parkinson's disease (PD) cognitive impairment using a comprehensive neuropsychological battery with…Action Verb Generation as a marker of cognitive function in Parkinson disease
Objective: We investigated action-verb generation in relation to cognitive function and motor severity in patients with Parkinson disease (PD). Background: PD causes speech and language…Global inhibitory control in PD is impaired ON dopaminergic medication but not ON STN-DBS
Objective: The aim of our study is to obtain a better understanding of how DA and STN-DBS modulate basal ganglia (BG) pathway functions. Background: Patients…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.