Pupillary autonomic dysfunction and oculomotor characteristics of multiple system atrophy
Objective: To investigate the pupillary autonomic function and oculomotor characteristics of patients with multiple system atrophy (MSA). Background: MSA is a debilitating neurodegenerative disorder with…Motor and cognitive deficits in a mouse model of tauopathy with tau isoforms imbalance: Potential therapeutic strategies
Objective: This work investigates motor phenotypes and neurochemical changes in a mouse model of tauopathy linked to tau mis-splicing. We sought to validate a potential…Diffusion magnetic resonance imaging for predicting the severity of Progressive supranuclear palsy
Objective: The current study proposed to build a prediction model of clinical severity from the combination of multiple diffusion tensor derived indices in patients with…Olfactory testing in Parkinson plus syndromes
Objective: To determine the diagnostic utility of olfactory testing in patients with neurodegenerative Parkinsonism. Background: Olfactory dysfunction can be identified in the vast majority of…Progressive Supranuclear Palsy and Eye of the Tiger Sign
Objective: To report a typical progressive supranuclear palsy case with "eye of the tiger sign" on MRI Background: Progressive supranuclear palsy (PSP); is a degenerative…PROMESA: A randomised, double-blind, placebo-controlled trial to evaluate the progression rate of MSA under EGCG supplementation as anti-aggregation-approach
Objective: To evaluate the safety and tolerability of epigallocatechin gallate (EGCG) in high doses and its efficacy to slow down disease progression in patients with…Postural deformities in Chinese patients with multiple system atrophy
Objective: The objective of our study was to investigate the frequency and clinical characteristics of the postural deformities in Chinese patients with multiple system atrophy…An atutopsy case of argyrophilic grain disease, clinically presenting with Parkinson dementia
Objective: We here reported argyrophilic grain disases (AGD) with clinical diagnosis of Parkinson dementia. Background: AGD is a four-repeat tauopathy and its accumulation (argyrophilic grain…Burden among Patients with Progressive Supranuclear Palsy
Objective: To quantify the economic costs and examine the most common co-morbidities of patients with progressive supranuclear palsy (PSP) in the United States. Background: PSP…Serum insulin-like growth factor-1 levels in parkinsonism or dementia disorders
Objective: To investigate serum insulin growth factor-1 (IGF-1) levels in neurodegenerative disease and to correlate clinical parameters. Background: IGF-1 is highly expressed in the central…
