Date: Sunday, October 7, 2018
Session Title: Parkinsonism, MSA, PSP (Secondary and Parkinsonism-Plus)
Session Time: 1:45pm-3:15pm
Location: Hall 3FG
Objective: The objective of our study was to investigate the frequency and clinical characteristics of the postural deformities in Chinese patients with multiple system atrophy (MSA).
Background: Previous studies have shown that postural deformities were not rare in patients with MSA. Up to now, there was no study available on the frequency and characteristics of postural deformities in Chinese MSA patients.
Methods: A total of 547 MSA patients were consecutive enrolled in the current study. Clinical features including age, sex, age at onset, disease duration, onset symptom and postural deformities were collected. The Unified Multiple System Atrophy Rating Scale (UMSARS) was used to evaluate the disease severity.
Results: Among the 547 MSA patients with mean disease duration of 2.72±1.42 years, 52 (20 males/32 females, 9.5%) patients presented with camptocormia; 17 (8 males/9 females, 3.1%) patients manifested Pisa syndrome; and 10 (4 males/6 females, 1.8%) patients presented with antecollis at the time of evaluation. Patients exhibited postural deformities were more common in MSA with predominant parkinsonism (MSA-P) subtype (P<0.05). In addition, MSA patients with camptocormia or antecollis had longer disease duration (P=0.001) and severe disease severity (UMSARS-I, UMSARS-II, UMSARS-IV, total UMSARS) (P<0.05) compared to those without. MSA patients with Pisa syndrome had severe disease severity (UMSARS-I, UMSARS-II, UMSARS-IV, total UMSARS) than those without Pisa syndrome (P<0.05).
Conclusions: Postural deformities were common (14.4%) in Chinese MSA patients, camptocormia come to the most common, especially in MSA-P patients. MSA patients with postural deformity have longer disease duration and severe disease severity.
To cite this abstract in AMA style:L. Zhang, B. Cao, Y. Zou, Q. Wei, R. Ou, B. Zhao, J. Yang, Y. Wu, H. Shanng. Postural deformities in Chinese patients with multiple system atrophy [abstract]. Mov Disord. 2018; 33 (suppl 2). https://www.mdsabstracts.org/abstract/postural-deformities-in-chinese-patients-with-multiple-system-atrophy/. Accessed November 29, 2023.
« Back to 2018 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/postural-deformities-in-chinese-patients-with-multiple-system-atrophy/