High voltage stimulation of the VIM thalamus mimicking PSP in a patient with ET + PD
Objective: To report a case of an 81 year-old male with ventral intermediate nucleus (VIM) deep brain stimulation (DBS) for essential tremor (ET) who developed…Focusing precision and lesion size in cerebello-thalamo-tractotomy by MR imaging-guided high intensity focused ultrasound (MRgFUS)
Objective: Focusing precision in tcMRgFUS tractotomy depends on the ability of the treatment system to compensate for acoustic field distortions induced by the patient skull.…Safety of deep brain stimulation for movement disorders: A single-centre long-term standardized recording and analysis
Objective: To analyze the long-term safety of Deep Brain Stimulation (DBS) procedures for patients with movement disorders. Background: DBS is currently indicated to treat several…Thalamic-subthalamic deep brain stimulation for refractory orthostatic tremor: A report of 3 cases
Objective: To report a case series of thalamic-subthalamic deep brain stimulation for the treatment of refractory orthostatic tremor. Background: Orthostatic tremor (OT) is a rare,…Ataxic gait in subjects with essential tremor and thalamic neurostimulation is caused by posteromedial current spread in the (sub)thalamic area
Objective: We aimed to disentangle a putative role of bilateral thalamic DBS in developing gait-ataxia in subjects with ET. Background: In ET patients with DBS,…Unilateral MR-guided high intensity focused ultrasound ablation of the cerebellothalamic tract in essential tremor
Objective: To report interim results of an ongoing trial of unilateral transcranial MR-guided high intensity focused ultrasound (tcMRgFUS) ablation of the cerebellothalamic tract (CTT) in…Comparison of cognitive and neuropsychological manifestations in patients with progressive supranuclear palsy (Psp) and Parkinson’s disease
Objective: 1) To compare the cognitive and neuropsychological manifestations between the patients with PSP and PD. 2) To find out the severity of caregivers distress…Hand skin temperature and its response to cooling in clinical differentiation of multiple system atrophy and Parkinson’s disease
Objective: To determine the value of testing hand temperature and its response to cooling for differential diagnosis of multiple system atrophy (MSA) versus Parkinson's disease…Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy
Objective: To assess the therapeutic efficacy of the caspase-1 inhibitor prodrug VX-765 on alpha-synuclein (α-syn) pathology and neuroprotection in a transgenic mouse model of multiple…Glucagon-like peptide 1 analogues for treating multiple system atrophy: A translational study
Objective: (i) To determine whether insulin resistance is a neuropathological feature of multiple system atrophy (MSA) and, (ii), to evaluate the therapeutic efficacy of the…
