Clinical efficacy of istradefylline on lower urinary tract symptoms in Parkinson’s disease: A prospective study
Objective: The aim of the present study was to determine the effects of istradefylline, adenosine A2A receptor antagonist on lower urinary tract symptoms (LUTS) in…Exercise induced analgesia is present in people with Parkinson’s disease
Objective: To investigate if exercise-induced analgesia (EIA) is present in people with Parkinson's disease (PD) compared to an age-matched control group. Background: Pain is a…Motor features and response to levodopa in Parkinson’s disease with normal olfactory function
Objective: The aim of this study was to evaluate motor features in the OFF and ON states and the acute levodopa response in Parkinson's disease…The effects of fluvoxamine maleate in a post-natal stress rat model of neurodegeneration
Objective: In this study, we investigated whether treatment of anxiety-like symptoms with Fluvoxamine maleate alleviates the neurotoxic effects of 6-OHDA in a Parkinsonian rat model.…Hyposmia as a predictor of non-motor symptom in patients with de novo Parkinson’s disease
Objective: To evaluate hyposmia as a predictor of non-motor features in patients with early Parkinson's disease (PD). Background: Hyposmia is quite a common finding in…Long-term efficacy of safinamide on mood in Parkinsonian patients with fluctuations
Objective: The present post-hoc analysis of the results of two pivotal trials (016 and 018) investigated the effects of safinamide 100 mg/day on mood in…Is continuous twenty four hour blood pressure monitoring a suitable tool in evaluating sleep disturbances in Parkinson’s disease?
Objective: To compare blood pressure (BP) changes in nighttime by continuous twenty four hour blood pressure monitoring (RR) as a postulated tool to describe sleep…The evolution of REM sleep behavior disorder in Parkinson’s disease: The DeNoPa cohort at 2-year follow-up
Objective: To investigate the evolution of REM sleep behavior disorder (RBD) in a cohort of at baseline de novo Parkinson's disease (PD) patients at follow-up…The prevalence of gastrointestinal disorders and non-motor symptoms in a cohort of patients with Parkinson’s disease
Objective: The aim of this investigation was to estimate the prevalence of gastrointestinal disorders (GID) and non-motor symptoms (NMS) in a cohort of a cohort…Non-motor symptoms trajectory in Parkinson’s disease: Magnitude and importance of the change
Objective: To determine the magnitude and clinical relevance of the change of non-motor symptoms (NMS) in Parkinson's disease (PD) patients over a 2-year follow-up. Background:…
