Depression, anxiety and quality of life in Multiple System Atrophy
Objective: To explore the features and determinants of depression and anxiety symptoms in multiple system atrophy (MSA) and the associations between mood dysfunction and quality…α-Synuclein Preformed Fibrils Induce Disruption of Myelin Basic Protein Expression in Primary Oligodendrocyte Culture; Deciphering Glial Pathology in Multiple System Atrophy
Objective: This research focuses on the impact of extracellular α-synuclein preformed fibrils (α-syn PFFs) on oligodendrocytes (OLGs) as a potential contributor exacerbating the pathology of…Profound reduction of DAT-SPECT signal in multiple system atrophy (MSA)
Objective: To evaluate the extent of degeneration in dopamine nerve terminal in striatum in the patients with MSA-P and MSA-C, and to compare the progression…Can the level of CSF Neurofilament Light Chain predict disease progression in Progressive Supranuclear Palsy?
Objective: To investigate whether the level of CSF Neurofilament Light Chain (NFL) can predict the speed of disease progression in patients with Progressive Supranuclear Palsy…Differential diagnosis of Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: The description of differential diagnostic features of PSP and PD in order to improve the diagnosis and the differential diagnosis of these diseases. Background:…Evaluation of a Radiographic Marker as a Diagnostic Tool For Progressive Supranuclear Palsy
Objective: To evaluate the sensitivity and specificity of a radiographic marker, midbrain to pons ratio, in brain MRI of Progressive Supranuclear Palsy (PSP) patients as…Progression of milestones by clinical types in progressive supranuclear palsy: a longitudinal observational study of a cohort of patients with PSP/CBD (the JALPAC project)
Objective: To elucidate the natural history of the PSP clinical phenotype Background: Recently, various clinical types of PSP have been reported, but details on their…Impulse control disorders in Parkinson’s disease; description of a New Zealand cohort
Objective: Impulse control disorders (ICDS) are a recognised complication of dopaminergic therapy for Parkinson’s disease. We wanted to assess the rates of ICDs in New…Brain metabolic patterns in progressive supranuclear palsy phenotypes
Objective: To describe changes in cerebral glucose metabolism in patients with different described clinical phenotypes of PSP and to correlate them with the clinical manifestations of the disease. Background:…Mutational analysis of COQ2 in Chinese patients with multiple-system atrophy
Objective: To investigate the involvement of COQ2 variants in Chinese sporadic cases with multiple-system atrophy. Background: Multiple-system atrophy (MSA) is a rapidly progressive neurodegenerative disease…
