Impact of prolonged temporal discrimination threshold on finger movements of Parkinson’s disease
Objective: In present study, we investigated the impact of temporal discrimination threshold (TDT) prolongation on simple repetitive finger tapping and dexterous finger movement in patients…Multidisciplinary group program integrating voice and dance movement therapy for Parkinson’s disease patients: Preliminary experience
Objective: To examine the effects of “Voice in Motion“ group therapy on movement, speech and QOL of PD patients. Background: Physical exercise and speech therapy…Dissecting the molecular mechanisms of Fyn-mediated levodopa induced dyskinesias
Objective: To investigate the crosstalk between D1 receptor (D1R) and the signaling of Fyn protein kinase in a mice model of levodopa (L-DOPA) induced dyskinesias…Olfaction and gray matter volume in Parkinson’s disease. A voxel-based morphometry study
Objective: To evaluate the relation between olfactory functioning and gray matter (GM) volume in patients with Parkinson's disease (PD). Background: Olfactory impairment is one of…Cellular senescence induced by paraquat drives neuropathology associated with Parkinson’s disease
Objective: To understand the role of cellular senescence in brain aging and neurodegeneration in Parkinson's disease models. Background: Although cellular senescence has been causally linked…Urate and homocysteine: Changes in motor and cognitive symptoms in newly diagnosed Parkinson’s disease
Objective: 1) To determine serum urate and homocysteine concentration at baseline, 18 and 36 months in control and PD participants. 2) To determine if urate…Dysregulated macroautophagy and mitochondrial dynamics in PD with glucocerebrosidase mutations
Objective: To investigate markers of macroautophagy and mitochondrial dynamics in fibroblasts and postmortem brain of Parkinson's disease (PD) patients with glucoerebrosidase (GBA1) mutations and controls.…Mitochondrial-nuclear interplay in single respiratory chain-deficient Parkinson’s disease neurons
Objective: To explore the role of the mitochondrial DNA (mtDNA) in the development of respiratory chain complex (CI-IV) deficiencies in the substantia nigra (SN) of…Kinematic analysis of repetitive finger movements and the effects of selegiline and pramipexole in early Parkinson’s disease
Objective: To characterize the features of bradykinesia in newly diagnosed patients with Parkinson's disease (PD) and the response to pramipexole and selegiline administration. Background: Motor…LC3 deacetylation by SIRT1 is involved in neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson’s disease
Objective: Our previous study has demonstrated that resveratrol (RV) enhanced clearance of misfolded α-synuclein proteins in cellular models of PD, with the activation of SIRT1…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.