Antidepressants in Huntington’s Disease: A Meta Analysis of Mood and Motor Outcomes with Placebo-controlled Trials
Objective: To evaluate the efficacy of antidepressants for depression in Huntington’s disease (HD). Background: Depression is highly prevalent in HD. Despite frequent clinical use of…Lipid Alterations in Central Nervous System and Plasma During Early Stages of Parkinson’s Disease
Objective: To identify early lipid alterations in a progressive mouse model of Parkinson’s disease (PD) and to determine whether peripheral lipid signatures reflect lipid changes…Rare Neurotoxicity of Cotrimoxazole A Movement Disorder Presentation In Elderly Patient
Objective: We report the case of an elderly woman with hyperkinetic movement disorders Background: Trimethoprim-sulfamethoxazole (TMP-SMX) is widely used for Pneumocystis jirovecii prophylaxis, but significant neurological toxicity…Clinical Characteristics and Functional Impact of Tremor in Patients with Multiple Sclerosis in Nepal: A Cross-Sectional Observational Study
Objective: To describe the clinical characteristics of tremor in multiple sclerosis (MS) patients in Nepal and assess its functional impact on daily living. To describe…A Meta-analysis of Tonic Motor Activation (TOMAC) Therapy for Restless Legs Syndrome
Objective: To evaluate the efficacy and safety of Tonic Motor Activation (TOMAC) therapy for adults with restless legs syndrome (RLS). Background: TOMAC is a novel,…Sex Differences in the Reported Prodromal Symptoms of Parkinson’s Disease (PD) in the Fox Insight Cohort
Objective: To identify differences in the self-reported prodromal symptoms of male vs female persons with PD (PwPD) in the Fox Insight (FI) cohort. Background: Early…GLP1R Expression and Parkinson’s Disease and Related Disorders in GLP-1RA–Treated Type 2 Diabetes
Objective: We tested whether interindividual differences in systemic GLP1R expression are associated with PDRD risk among adults with type 2 diabetes initiating GLP-1RAs. Background: Preclinical…Gait parameters, Imaging features, and CSF tap test in idiopathic Normal Pressure Hydrocephalus (iNPH) Is composite testing the way to go
Objective: To analyze the positive predictive values of specific imaging findings for CSF-TT responsiveness and shunt responsivenessTo determine whether composite diagnostic models incorporating CSF-TT and…Subthalamic Nucleus Deep Brain Stimulation Modulates Cortical Activation During Kinesthetic Illusion in Parkinson’s Disease: An fMRI Study
Objective: To investigate how subthalamic nucleus deep brain stimulation (STN-DBS) modulates cortical activation during kinesthetic illusion (KI) in Parkinson’s disease (PD). Background: There is increasing…Sudomotor Dysfunction in Patients With Normal and Abnormal Cardiac MIBG
Objective: We examined the pattern of sweat loss in patients with normal versus abnormal MIBG and considered the implications of this in predicting phenoconversion trajectory.…
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