Long-Term Instability of GPi Gamma Oscillations in Parkinson’s Disease: A Case Study
Objective: To characterize longitudinal changes in globus pallidus internus (GPi) finely tuned gamma (FTG) oscillations during chronic deep brain stimulation (DBS) in a patient with…Sudomotor Dysfunction in Patients With Normal and Abnormal Cardiac MIBG
Objective: We examined the pattern of sweat loss in patients with normal versus abnormal MIBG and considered the implications of this in predicting phenoconversion trajectory.…Pregnancy and Breastfeeding in Early-Onset Parkinson’s Disease:Therapeutic Challenges of Levodopa Monotherapy.A case Report.
Objective: To describe the clinical course and treatment challenges of early-onset Parkinson’s disease (EOPD) during pregnancy and breastfeeding Background: Parkinson’s disease (PD) is rare in…THD (Tyrosine Hydroxylase Deficiency) in a 39-Year-Old Woman with Early-Onset Dystonia
Objective: To report a case of tyrosine hydroxylase deficiency (THD), a rare neurometabolic disorder that disrupts catecholamine biosynthesis. This case report highlights common neurologic abnormalities,…Juvenile-Onset Parkinsonism With Bilateral Striatal Necrosis Associated With a Pathogenic MT-ND3 Mitochondrial Variant
Objective: To report a case of juvenile-onset parkinsonism associated with bilateral striatal necrosis and a pathogenic MT-ND3 mitochondrial DNA variant, emphasizing an atypical mitochondrial phenotype…Early Manifestations of Cerebellar Ataxia with Neuropathy and Vestibular Areflexia Syndrome (CANVAS) Include Dystonic Laryngeal Phenomena
Objective: To describe four patients in whom laryngeal dystonia manifesting as cough and spasmodic dysphonia preceded Cerebellar Ataxia with Neuropathy and Vestibular Areflexia Syndrome (CANVAS)…A 6-month Pilot Study of Disease-Modifying Potential of Long-term Transcutaneous Auricular Vagus Nerve Stimulation in Parkinson’s Disease
Objective: To investigate the efficacy and potential disease-modifying effects of of long-term transcutaneous auricular vagus nerve stimulation(taVNS) in patients with early-stage Parkinson's Disease(PD). Background: PD currently lacks established disease-modifying…Immune-mediated Chorea in Antiphospholipid Syndrome: Normalization of FDG-PET and Neurofilament as Markers of Treatment Response.
Objective: To present a case where FDG-PET and neurofilament findings help portray the reversibility of neuronal damage in antiphospholipid syndrome (aPL). Background: Chorea is the most common movement disorder in aPL and often an initial manifestation, although…A Meta-analysis of Tonic Motor Activation (TOMAC) Therapy for Restless Legs Syndrome
Objective: To evaluate the efficacy and safety of Tonic Motor Activation (TOMAC) therapy for adults with restless legs syndrome (RLS). Background: TOMAC is a novel,…Sex Differences in the Reported Prodromal Symptoms of Parkinson’s Disease (PD) in the Fox Insight Cohort
Objective: To identify differences in the self-reported prodromal symptoms of male vs female persons with PD (PwPD) in the Fox Insight (FI) cohort. Background: Early…
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