Disease Burden Profile of Patients with Spinocerebellar Ataxia in China: A Real-World Registry Study (2025)
Objective: To analyze the clinical characteristics, diagnostic pathways, and socioeconomic impact on newly registered SCA patients in China during the year 2025. Background: Spinocerebellar ataxia…Spatiotemporal Trajectories of Plasma Biomarkers and Diffusion MRI Metrics in Parkinson’s Disease
Objective: To investigate the spatiotemporal dynamics of multimodal biomarkers and their role in early prediction of cognitive decline. Background: Cognitive impairment is a major source…Dual-site rTMS for Essential Tremor
Objective: To evaluate the safety and therapeutic potential of dual-site repetitive transcranial magnetic stimulation (rTMS) targeting the supplementary motor area (SMA) and cerebellum in medication-refractory…Functional neurosurgery in Parkinson’s disease: Effects on quality of life.
Objective: This study aims to determine the impact of surgical procedures on quality of life in patients with PD using the PDQ-39 questionnaire. Background: Parkinson's…Functional Improvement Following Early GPi-DBS for Moderate-Stage Atypical KMT2B Dystonia: A Case Report in a 13-Year-Old Girl
Objective: To report clinical trajectory and functional improvement of a child with atypical KMT2B-related dystonia following bilateral GPi-DBS performed at a moderate disease stage. Background:…Relationships of serum & CSF Transcobalamin Receptor Antibodies to CSF vitamin B12, holotranscobalamin and clinical progression in Parkinson’s disease
Objective: To measure serum & CSF transcobalamin receptor antibodies (CD320ab) in patients with early Parkinson’s disease (PD) and to assess their relationships to CSF vitamin…Longitudinal Weight/BMI Trajectories and Their Clinical Impact on Parkinson’s Disease.
Objective: To evaluate longitudinal weight/BMI trajectory classes in PwP and their association with motor progression and quality of life (QoL). Background: Weight homeostasis is frequently…Performance of the functional staging of Parkinson’s disease using the Neuronal aSynuclein Disease Integrated Staging System (NSD-ISS) in the Critical Path for Parkinson’s (CPP) Integrated Parkinson’s Database
Objective: To evaluate the utility of the NSD-ISS for clinical staging of Parkinson’s disease (PD) by examining stage distribution, longitudinal stage transitions, and demographic predictors…Prognostic Impact of GBA Variants on Mortality in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: This systematic review and meta-analyses aim to synthesize longitudinal evidence of GBA variants as a prognostic factor for all-cause mortality in Parkinson’s disease (PD).…Taekwondo Training with External Focus of Attention as a Complex Motor Intervention in Parkinson’s Disease: A Pilot Study
Objective: To examine the feasibility and effects of an 8-week Taekwondo (TKD) training emphasizing multidirectional, externally focused, and cognitively challenging motor training on balance and mobility in people with Parkinson’s disease (PwPD). Background: Conventional…
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