Extended long-term follow-up of adaptive deep brain stimulation in Parkinson’s disease
Objective: To evaluate the extended long-term durability, programming stability, and safety of adaptive deep brain stimulation (aDBS) in people with Parkinson’s disease (PD). Background: Adaptive DBS is a recently available enhancement to continuous DBS (cDBS) that dynamically adjusts stimulation amplitude based on neural…fMRI Activity during Working Memory Manipulation is Associated with Caudate Integrity in Early Parkinson’s Disease
Objective: This study aimed to determine whether reduced dopaminergic integrity and increased iron deposition in the caudate are associated with altered BOLD activation during high…Poststroke Movement Disorders: Clinical, Neuroimaging and Electrophysiological correlates
Objective: To study the phenotypes of post stroke movement disorders (PSMDs) and examine their correlations with neuroimaging and electrophysiology. Background: Different stroke locations lead to…TMEM106B Fibrils Potentiate Pathological α-Synuclein Aggregation in Parkinson’s Disease
Objective: To determine whether transmembrane protein 106B (TMEM106B) fibrils promote α-synuclein (α-syn) aggregation and to elucidate the molecular basis of this interaction in Parkinson’s disease…Optimizing Institutional Long-Term Care in Advanced Parkinson’s and Other Neurodegenerative Disease: The OPTICARE Study
Objective: To analyze and improve institutional long-term care (LTC) structures for patients with advanced PD and AD by identifying modifiable determinants of care integration, QoL,…Safety and Effect of Ecopipam During the First 8 Weeks of Treatment for Tourette Syndrome: A Post Hoc Analysis
Objective: To assess the safety profile and effect of ecopipam, a selective dopamine D1 receptor antagonist, during the first 8 weeks of therapy for Tourette…Effects of Modafinil on Motor and Non‑Motor Outcomes in Parkinson’s Disease: A Meta‑Analysis of Randomized, Placebo‑Controlled Trials
Objective: To determine the efficacy and safety of modafinil on motor and non-motor outcomes in Parkinson’s disease (PD) using evidence exclusively from randomized placebo‑controlled clinical…Association between Sleep Behaviors and Age at Onset of Parkinson’s Disease
Objective: To investigate the associations between multiple sleep behaviors and the age at onset (AAO) of Parkinson’s disease (PD) using the UK Biobank. Background: Sleep…Disease Burden Profile of Patients with Spinocerebellar Ataxia in China: A Real-World Registry Study (2025)
Objective: To analyze the clinical characteristics, diagnostic pathways, and socioeconomic impact on newly registered SCA patients in China during the year 2025. Background: Spinocerebellar ataxia…Characteristics of participants of the Australian National Disability Insurance Scheme with Parkinson’s disease
Objective: To evaluate the demographic characteristics, goals and funding of participants with Parkinson’s disease (PD) in the Australian National Disability Insurance Scheme (NDIS). Background: The…
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