Posturography as an objective measure of disease progression and prognostication in Progressive Supranuclear Palsy
Objective: To determine the usefulness of posturography as an objective measure of disease progression and prognostication on Progressive Supranuclear Palsy (PSP). Background: To date, interventional…Novel CACNA1A splice site variant associated with cerebellar ataxia and mild cognitive impairment; case report of Czech family.
Objective: To describe a case of two related individuals with cerebellar ataxia with a novel variant in the calcium voltage-gated channel subunit alpha1-A (CACNA1A) gene.…Cholinergic subtyping in Parkinson disease: differential 2-year interval changes
Objective: To investigate 2-yr interval change in cholinergic transporters in biology-based cholinergic subgroups using serial VAChT [18F]FEOBV brain PET in Parkinson’s disease (PD). Background: Current…Chorea improvements over time with once-daily valbenazine treatment in adults with Huntington disease
Objective: To describe the effects of valbenazine (VBZ) over time on chorea in adults with Huntington disease (HD). Background: The Ph3 KINECTTM-HD (NCT04102579) trial met…Spectrum of Hereditary Spastic Paraparesis (HSP): A study from India
Objective: To explore the genetic spectrum of hereditary spastic paraparesis in Indian patients. Background: HSP belongs to a heterogenous group of monogenic neurological disorders with…Pre-surgical correlates of QoL (PDQ-39) in a DBS eligible PD population
Objective: To investigate the pre-surgical correlates of quality of life (QoL) in patients with Parkinson's disease (PD) eligible for deep brain stimulation (DBS). Background: Optimizing…Ultra long-term outcome of deep brain stimulation (DBS) compared to botulinum toxin (BoNT) treatment in cervical dystonia (CD)
Objective: To compare residual symptoms and disease-specific quality of life (DS-QoL) in CD patients treated with DBS, or BoNT injections alone, for minimum 3 years.…Motor phenotype and disease burden among Parkinson’s disease patients of Addis Ababa, Ethiopia.
Objective: This study aims to characterize the motor phenotype of Parkinson’s disease (PD), compare disease severity and to determine quality of life among the different…Hemidystonia of cerebellar origin
Objective: To report the case of a patient developing hemidystonia in the course of cerebellar hemorrhage. Background: About 1-4% of strokes may include movement disorders,…The efficacy of dopamine agonists or monoamine oxidase type B inhibitors as monotherapy in patients with early Parkinson disease: A network meta-analysis
Objective: This study aimed to investigate the effectiveness of dopamine agonists or monoamine oxidase type B inhibitors (MAOB-I) as monotherapy in patients with early Parkinson's…
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