Analysis of Patellar Reflex in Parkinson Disease Patients after an Acupuncture Treatment Protocol – Case Series Study
Objective: To analyze the behavior of patellar reflexes in four Parkinson's Disease patients undergoing an acupuncture treatment protocol. Background: The investigation of rigidity physiology in…Sleep disorders in Parkinson’s disease
Objective: to specify the clinical features of sleep disorders in patients with PD and their impact on quality of life indicators; assessment of the relationship…A Randomized, Double-blind, Phase 2a Clinical Trial to Study the Efficacy and Safety of Lamotrigine for Treatment of Patients with Dementia with Lewy Bodies
Objective: This proof-of-concept clinical trial will test the efficacy and safety of lamotrigine compared to placebo in patients with dementia with Lewy bodies (DLB). Background:…Melatonin Modulates NLRP3 Inflammasome Activation through TLR2 to Protect Against Parkinson’s Disease
Objective: This study aims to investigate the impact of MLT on inflammation signaling pathway mediated by TLR2 in α-synuclein (α-syn) overexpressed BV2 cells and PD…Essential Tremor: The Relationship Between Hand Dominance and Tremor Severity by MVPA
Objective: The objective of this study was to analyze task-based functional Magnetic Resonance Imaging (task-fMRI) to investigate neural activity patterns in individuals diagnosed with Essential…Sphingomyelinase Activity in Patients with Sporadic Parkinson’s Disease
Objective: To measure the sphingomyelinase (ASMase) activity in sporadic PD patients and matched healthy controls and identify any clinical or biological correlation with disease’s severity.To…Gut Microbiota May Alter Glucose Metabolism in Patients with Parkinson’s Disease
Objective: To compare the gut microbiota in patients with Parkinson’s disease (PD) and healthy controls and predict the functional pathways associated with these differences. Background:…Polyamine pathways: a promising frontier for biomarkers and therapeutic targets in Parkinson’s disease (PD)
Objective: To systematically modulate polyamine (PA) metabolic pathways and investigate PA biomarker findings in PD using Drosophila melanogaster over-expressing human wild-type α-synuclein gene (hSNCA). Our…Opicapone as First-Line Strategy for the Treatment of Wearing-off in Korean Patients with Parkinson’s Disease
Objective: This study aimed to explore the efficacy of opicapone (OPC) 50 mg versus an extra 100 mg levodopa (L-dopa) dose to treat early wearing-off…Gait Digital Outcomes Exploration from Continuous Real-World Recordings in Parkinson’s Disease
Objective: To measure how people with Parkinson's disease (PD) feel, function, and survive, derived from continuous recordings with a wearable ankle inertial device in a real-world…
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