Evaluation of Swallowing and Cough Function in older Patients with Parkinson’s Disease
Objective: This study aimed to characterize swallowing and cough function in older patients with Parkinson’s disease (PD) using a multidimensional assessment. Background: With population aging,…Semiquantitative [¹²³I]FP-CIT SPECT metrics combined with machine learning improve clinical differentiation of parkinson’s disease and atypical parkinsonian syndrome
Objective: To evaluate the capacity of semiquantitative striatal [¹²³I]FP-CIT SPECT-derived metrics to improve the clinical differentiation of degenerative parkinsonism through an integrated machine learning model.…Robust Location-Agnostic Turn Speed Estimation to Ensure Consistent Remote Monitoring of Gait Impairment in Parkinson’s Disease
Objective: To determine if a novel, location-agnostic algorithm provides consistent turn-speed measures in people with Parkinson’s (PwP) across sternum, lower back, and thigh locations. Background:…Pesticide Exposure and Motor Severity in Parkinson’s Disease in a Mexican Population: A Retrospective Longitudinal Cohort Study
Objective: To evaluate whether pesticide exposure is associated with greater baseline motor severity and accelerated longitudinal motor progression in Mexican patients with Parkinson’s disease (PD).…Expanding the Spectrum of Non Motor Symptoms in Dystonia: Focus on Autonomic Signs and Pain
Objective: To assess autonomic nervous system (ANS) involvement and pain prevalence among non-motor symptoms (NMS) in different types of dystonia Background: Prevalence and functional impact…Risk stratification study of fluid biomarkers for alpha-synucleinopathy with dementia
Objective: This study focuses on mixed pathology of α-synucleinopathy and Alzheimer’s disease(AD), analyzing the relationships among biomarkers, genetic factors, and cognitive function in order to…Basal Ganglia Germinoma (BGG) Presenting as Hemidystonia
Objective: We describe an unusual case of progressive right-sided hemidystonia with accompanying imaging and video. Background: Intracranial germinomas most often arise from midline structures, but…Effects of Modafinil on Motor and Non‑Motor Outcomes in Parkinson’s Disease: A Meta‑Analysis of Randomized, Placebo‑Controlled Trials
Objective: To determine the efficacy and safety of modafinil on motor and non-motor outcomes in Parkinson’s disease (PD) using evidence exclusively from randomized placebo‑controlled clinical…Chronic Vanadium Exposure Promotes Memory Impairment and Aggregation of Alpha-Synuclein, Tau and Amyloid Beta in Mouse Brain
Objective: In this study, we hypothesized that prolonged vanadium exposure may be a potential risk factor for Alzheimer's and Parkinson's diseases. Background: The interaction between…Use of Mucuna Pruriens (M. Pruriens) in People with Parkinson’s Disease (PwPD)
Objective: To characterize M. pruriens use among local (primarily Argentinian) PwPD. Background: M. pruriens is a leguminous plant used in Ayurvedic medicine to treat Parkinsonism…
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