Exploring the Relationship Between Circadian Disruption, Depression and Suicidal Ideation in People with Huntington’s Disease (Mind & Clock Study)
Objective: To examine the relationship between circadian and sleep disruptions and depressive symptoms and suicidal ideation in people with Huntington’s Disease (PwHD) using scale-based and…Dual-site rTMS for Essential Tremor
Objective: To evaluate the safety and therapeutic potential of dual-site repetitive transcranial magnetic stimulation (rTMS) targeting the supplementary motor area (SMA) and cerebellum in medication-refractory…Real-World Clinical Outcomes and Patient Experience Following Hybrid DBS Conversion to a Neurostimulator with Advanced Current Steering
Objective: In this report, we describe preliminary real-world clinical outcomes and patient experience following hybrid DBS conversion procedures at our center. Background: Hybrid replacement procedures…Skin Biopsy for Phosphorylated Alpha-Synuclein and DAT Imaging in Patients Diagnosed with Psychogenic Parkinsonism
Objective: Objective:Describe the results of skin biopsy for phosphorylated alpha-synuclein (P-SYN) and dopamine transporter (DAT) imaging in patients previously diagnosed with psychogenic parkinsonism (PP) and…Plasma Exosomal Cytokines as Longitudinal Biomarkers and Predictors of Parkinson’s Disease Progression
Objective: To determine whether plasma exosomal cytokines can serve as stable biomarkers of disease progression in Parkinson’s disease (PD) and to evaluate their utility in…Local Field Potentials (LFP) Insights in the Treatment of X-linked Dystonia-Parkinsonism with Deep Brain Stimulation of the Subthalamic Nucleus
Objective: To demonstrate sustained improvement in parkinsonism and dystonia in patients with X-linked Dystonia-Parkinsonism (XDP) after deep brain stimulation (DBS) of the subthalamic nucleus (STN)…Patient-centered Parkinson’s services and integrated primary care in southern Ghana: patient and caregiver perceptions from a cross-sectional survey
Objective: To evaluate patients’ and caregivers’ perceptions of patient-centered care for persons with Parkinson’s disease (PwPD) across three healthcare facilities in southern Ghana, and to…Risk of Ischemic Cerebrovascular Events in Patients with Deep Brain Stimulation for Parkinson’s Disease: A Cohort Study
Objective: To longitudinally assess the risk of ischemic cerebrovascular events in patients undergoing DBS Background: Longitudinal data on the potential impact of DBS on long-term…Smell as a Diagnostic Signature: Systematic Review and Meta-Analysis of UPSIT Accuracy in Distinguishing Parkinson’s Disease from Essential Tremor
Objective: To evaluate the diagnostic performance of the University of Pennsylvania Smell Identification Test (UPSIT) in differentiating Parkinson’s disease (PD) from essential tremor (ET) using…Multimodal Imaging in Cervical Dystonia with Botulinum Toxin Treatment: A Pilot 5.0T MRI and 99mTc-MIBI SPECT/CT Study
Objective: To comprehensively investigate structural, vascular, and metabolic alterations in cervical dystonia (CD) patients using ultra-high-field 5.0T magnetic resonance imaging (MRI) and 99mTc-MIBI SPECT/CT. Background:…
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