Short-term effect of continuous positive airway pressure in MSA patients with sleep disordered breathing
Objective: SBD are frequent in MSA, mainly represented by inspiratory stridor, obstructive and central sleep apnea/hypopnea syndrome (SAS), or hypopneaimpacting the quality of sleep. A…POU4F1-related ataxia: phenotyping of a rare genetic ataxia.
Objective: To illustrate the symptoms, signs, and videotaped examination of a rare genetic disorder. Background: POU4F1 encodes a transcription factor involved in nervous system development.…AAV5-miHTT gene therapy mediates sustained mutant huntingtin lowering in brain and cerebrospinal fluid of Huntington’s disease minipigs up to 5 years
Objective: Our objective is to assess long-term safety of and durability of an adeno-associated viral vector serotype 5 encoding an engineered miRNA (AAV5-miHTT) targeting human…Efficacy and safety of Mexiletine versus Placebo in patients with myotonia: A Systematic Review and Meta-analysis
Objective: We conducted this study to be the first systematic review and meta-analysis to investigate the efficacy and safety of mexiletine in the treatment of patients…Cerebrospinal fluid biomarkers for diagnosis of Parkinson’s disease: a systematic review and network meta-analysis
Objective: In this study, we intended to use network meta-analysis to compare the diagnostic performances of different CSF biomarkers in the diagnosis and differential diagnosis…Education level and the onset and severity of symptoms in Huntington’s disease
Objective: The current study aimed to investigate the effect of educational level on the clinical characteristics of Chinese patients with Huntington’s disease (HD). Background: Education…Placebo response in Parkinson’s disease (PD) is predicted by expression levels of a specific brain network
Objective: To determine whether baseline expression levels for the previously validated sham surgery-related metabolic pattern (SSRP) can be used to predict the magnitude of the…Machine learning classifies Parkinson’s Disease and Progressive Supranuclear Palsy on saccade, pupil, and blink measures during a naturalistic free-viewing task
Objective: Eye tracking has been suggested as a source of prospective biomarkers in Parkinson’s Disease (PD), and recent work has demonstrated the use of machine…Chinese medicine pattern diagnostic criteria in clinical and epidemiological studies of Parkinson’s disease: a systematic review
Objective: To summarize the diagnostic criteria of Chinese medicine patterns (CMPs) adopted by clinical and epidemiological studies of Parkinson’s disease (PD). Background: One major reason…Connectomic DBS informed multifocal transcranial direct current stimulation (tDCS) in Parkinson’s Disease: a crossover double blinded study
Objective: To determine if non-invasive neuromodulation of a network previously identified through invasive neuromodulation could improve motor symptoms in Parkinson's disease (PD). Background: A recent…
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