Uncovering the mechanisms of genotype by environment interaction in an idiopathic Parkinson’s disease model in Drosophila
Objective: To identify the genetic basis and the molecular mechanisms that underlie the susceptibility of developing motor defects in response to exposure to pesticides in…MRgFUS thalamotomy in dystonic and essential tremor: a prospective study with one year follow up
Objective: The primary objective of this study was to evaluate the effectiveness of MRgFUS thalamotomy in patients with Dystonic Tremor (DT) compared with patients with…Remote monitoring of physical activity in Progressive Supranuclear Palsy (PSP) using wearable sensors
Objective: To remotely monitor physical activity in people with PSP and to correlate it with disease progression on the modified PSP Rating Scale (mPSPRS-21). Background:…Analysis of the relationship between acoustic measures and VHI score
Objective: To examine whether there is a relationship between acoustic measurements extracted from audio recordings of sustained vowel /a/ of PWP and their VHI scores.…Clinical progression in males and females with early treatment-naive Parkinson’s disease
Objective: To investigate differences in the progression of motor and non-motor symptoms and striatal degeneration between males and females with Parkinson’s disease (PD). Background: Biological…Screening and Treatment of Depression in Parkinson’s Disease Within Movement Disorders Centers
Objective: Implement depression screening using a validated instrument for people with Parkinson’s (PWP) as part of standard of care in the specialist movement disorders setting…Synaptic density and α-synuclein oligomers in skin biopsies: differences between idiopathic and GBA-linked Parkinson’s disease
Objective: To compare α-synuclein oligomers and synaptic density (SD) in skin biopsies from PD and GBA-PD. Background: Previous research [1] reported α-synuclein oligomers within synaptic terminals of autonomic fibers in…iCARE-PD: a multinational multicenter feasibility study of Integrated Care Networks in Parkinson disease
Objective: To evaluate the implementation of a novel pragmatic care delivery model for people living with Parkinson’s disease (PwP) Background: The intrinsic complexity of care…Putting the patient’s voice at the venter: Tracking the impact of botulinum neurotoxin therapy for movement disorders using patient-reported outcomes
Objective: To investigate how patient reported outcomes (PROs) perform to document the effects of a botulinum neurotoxin (BONT) treatment of movement disorders in the clinical…Vagus nerve degeneration in Parkinson’s disease: correlation with autonomic symptoms and pupillography
Objective: To test the hypothesis that vagus nerve (VN) atrophy is pronounced in the body-first subtype of Parkinson’s disease (PD) and coincides with pupillary dysfunction.…
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