What Non-Genetic Parkinson’s Disease Risk Factors are Africans Exposed To? A Scoping Review
Objective: We set out to catalogue the risk factors patients with Parkinson’s Disease (PD) in Africa are exposed to. Background: Parkinson's disease (PD) is recognized…Urate Levels and Risk of Parkinson’s Disease:A Two-Sample Mendelian Randomization Study
Objective: To investigate the causal relationship between circulating serum urate levels and the risk of Parkinson's disease (PD) using a two-sample Mendelian randomization (MR) approach.…Mild Motor Impairments in Rapid Eye Movement Behavior Disorder: Tremor and Bradykinesia
Objective: We investigated patients with RBD to identify mild motor impairments through the objective quantification of sensitive motor control assays. Background: It is established that…One day accelerated 10 Hz rTMS for Focal Hand Dystonia: A Phase II Clinical Trial
Objective: To evaluate the efficacy of four sessions of 10 Hz repetitive transcranial magnetic stimulation delivered in one day (rTMS) to patients with focal hand…The Correlation Between Serum Uric Acid Levels And The Severity Of Parkinson’s Disease
Objective: This study aims to analyze the correlation between serum uric acid levels and the severity of Parkinson's disease. Background: Uric acid has been implicated…Beyond Parkinson’s Disease, Impulse Control Dysregulation: The Psychosocial Correlates of Problematic Internet Use
Objective: To determine the prevalence of problematic internet use and associated psychosocial correlates as a phenotype of impulse control dysregulation among undergraduates. Background: Impulse control…Differential Oculomotor Patterns in Parkinson’s Disease and Multiple System Atrophy With Predominant Parkinsonism
Objective: To investigate the value of oculomotor function assessment in differentiating Parkinson’s disease (PD) from multiple system atrophy with predominant parkinsonism (MSA-P). Background: PD and MSA-P share…Ulixacaltamide Demonstrates Superiority Over Placebo as Monotherapy and as Add-on to Propranolol in Essential Tremor: Phase 3 ESSENTIAL3 Study 1
Objective: To evaluate efficacy of ulixacaltamide, a selective T-type calcium channel modulator, versus placebo in adults with essential tremor (ET) as monotherapy and as add-on…Neuropsychiatric Symptoms in Lewy Body Disease: Monoaminergic Activity and Resting State Networks
Objective: Investigating how neuropsychiatric symptoms (NPS)—depression, anxiety, and apathy—relate to functional connectivity between monoaminergic nuclei and the limbic network (LN), default mode network (DMN), and…Targeting c-Abl/Drp1-Dependent Mitochondrial Fission: Neuroprotective Effects of Berberine Chloride in Parkinson’s Disease Models
Objective: To investigate the neuroprotective potential of berberine chloride in Parkinson’s disease (PD) by modulating pathological mitochondrial fission through c-Abl–mediated Drp1 phosphorylation using integrated bioinformatics,…
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