Bidirectional associations between seizures and parkinsonism: a retrospective case series
Objective: Within a single center, describe individuals with parkinsonism who develop seizures and vice versa based on epilepsy and movement disorders evaluation. Background: While neurodegeneration…Investigating Hippocampal Subfield and Amygdala Volumes in Parkinson’s Disease with Anxiety
Objective: To determine whether structural changes in the hippocampus and amygdala are associated with anxiety in Parkinson’s disease (PD), and to identify whether these alterations…Integrating Multidisciplinary, Family-Centered Care to Optimize Functional Outcomes in Children with Cerebral Palsy.
Objective: Optimal management of Cerebral Palsy requires coordinated, evidence-based interventions that address both motor and non-motor domains across the lifespan. Background: Randomized controlled trials (RCTs)…Beyond Parkinson’s Disease, Impulse Control Dysregulation: The Psychosocial Correlates of Problematic Internet Use
Objective: To determine the prevalence of problematic internet use and associated psychosocial correlates as a phenotype of impulse control dysregulation among undergraduates. Background: Impulse control…Early Caudate Dopaminergic Loss as an Imaging Biomarker of Cognitive Impairment in Parkinson’s Disease: A Longitudinal Analysis
Objective: The primary objective was to determine whether early pre-synaptic caudate denervation, measured using 123 I ioflupane SPECT quantitative metrics, provides independent and incremental prognostic value…Cognitive Progression in Elderly Essential Tremor Patients: Evidence from an 18-Month Prospective Cohort
Objective: Essential tremor (ET) is one of the most prevalent neurological disorders and has increasingly been linked to cognitive dysfunction. However, most existing data regarding…Micro- and Nanoplastics in Parkinson’s Disease Pathogenesis An Emerging Environmental Risk Factor
Objective: To synthesize current experimental and translational evidence supporting the hypothesis that micro- and nanoplastics (MNPs) may contribute to Parkinson’s disease (PD) pathogenesis through neuroinflammatory…Proposal of Anatomo-Functional Tremor Patterns for Ultrasound-Guided Botulinum Toxin Infiltration
Objective: To propose a practical anatomo-functional framework for ultrasound-guided BoNT-A infiltration in upper limb tremor based on tremor biomechanics. Background: Botulinum toxin type A (BoNT-A)…Skin Tau Quantification as a Potential Degeneration Biomarker in Parkinson’s Disease
Objective: This cross-sectional observational study aims to quantify total skin Tau levels in Parkinson’s disease (PD) patients and explore their association with clinical symptoms. Background:…Repurposing Rifabutin for Neuro-Metabolic Disorders: AMPK-PGC-1α-Driven Mitochondrial Protection in Diabetes Associated Parkinsonism
Objective: To assess the role of rifabutin in restoring mitochondrial function and energy balance through modulation of the AMPK–PGC-1α signaling pathway in diabetes-related Parkinsonism. Background:…
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