Natural history and disease progression biomarkers of multiple system atrophy: the ASPIRE-MSA study
Objective: To evaluate multiple system atrophy (MSA) disease progression on a panel of candidate MSA biomarkers pre-selected for their putative involvement in the pathophysiology of…Sacral Mass Lesion Mimicking Atypical Foot Dystonia In Parkinsonian Pa tient
Objective: Describe an unusual presentation of leg posturing and dystonic features in a patient with diagnosis of atypical parkinsonism, which was ultimately found to be…Association Between Anticholinergic Burden, MCI, and Cholinergic Denervation
Objective: To characterize the relationship between anticholinergic burden (ACB), mild cognitive impairment (MCI), and its underlying cholinergic pathology. Background: MCI is a common phenomenon in…Association between dysphagia and body mass index and his impact on the severity of anxiety in patients with Parkinson Disease
Objective: To describe the relation between dysphagia and body mass index and the increase in anxiety and depression in patients with parkinson’s disease. Background: Parkinson’s…Correlation between dose of dopamine replacement therapy and King’s Parkinson’s Disease Pain Scale in Mexican Patients with Parkinson’s Disease
Objective: Investigate the relationship between the dose of dopamine replacement therapy (DRT) and pain severity as measured by the King's Parkinson's Disease Pain Scale (KPPS)…Impact of non-pharmacological strategies on progression in Parkinson’s Disease and Cognitive Impairment.
Objective: to determine the Impact of non-pharmacological strategies on progression in Parkinson's Disease and Cognitive Impairment. Background: PD is the second most common neurodegenerative disorder,…Clinical toolkits to improve conversations about Parkinson’s dementia
Objective: To co-produce, with people living with Parkinson’s and professionals, a pair of toolkits to improve conversations about Parkinson’s dementia in the clinic: one for…Clinical correlates of olfactory dysfunction in Huntington’s disease
Objective: To assess olfactory dysfunction in patients with HD and correlate the degree of olfactory dysfunction with symptomatic domains of HD. Background: Olfactory dysfunction is…Machine Learning Prediction of Gait Dysfunction from DTI Multi-Spectral Diffusion Weighted Imaging ROIs
Objective: To compare the performance of various machine learning techniques, including LDA, k-NN, SVM, MLP, Long Short-Term Memory (LSTM), Gradient Boosting Machines (GBM), Random Forest,…Modifying clinical and electrophysiological parameters through Transcranial pulsed current stimulation (tPCS) in Huntington disease
Objective: 1. To assess brain network dysfunction of Huntington disease (HD). 2. To evaluate the effectiveness of 2-week home-based chronic non-invasive transcranial brain stimulation to…
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