Polymorphisms in Prosaposin gene are associated with familial and early-onset Parkinson’s disease: A case-control association study and meta-analysis
Objective: To investigate the role of the PSAP gene in PD patients in Taiwan, including familial PD and early-onset Parkinson’s disease. Background: Mutations in the…Altered visual network dynamics associated with freezing of gait in Parkinson’s disease
Objective: We aimed to characterize the dynamic functional connectivity (DFC) in people with FOG based on high temporal-resolution functional MRI (fMRI). Background: Freezing of gait…Exploring Young people’s role in providing relief to grandparents affected with Alzheimer
Objective: In some families, children never know that their parents or grandparents are affected by the Parkinson’s Disease (PD). Whatever be the way that Movement…A secretory vesicle failure in Parkinson’s disease occurs in human platelets
Objective: Since platelets use similar, if not the same, mechanisms to accumulate serotonin (5-HT) as dopaminergic neurons to store DA in their VS; we wonder…Safety of opicapone after 5 years of post-marketing experience worldwide
Objective: To review the safety data of opicapone (OPC) after five years of marketing experience worldwide Background: OPC is a once-daily catechol-O-methyltransferase (COMT) inhibitor proven…Alprazolam reduces freezing of gait and improves freezing-related gait measures
Objective: We investigated the effect of acutely reducing anxiety with the benzodiazepine, Alprazolam, on freezing of gait (FOG) in patients with Parkinson’s disease (PD). Background:…EFFECTS OF DOPAMINERGIC MEDICATION ON REACTIVE AND PROACTIVE INHIBITORY CONTROL
Objective: In this study, we aim to address the effects of dopaminergic treatment (DT) on the two domains of motor inhibition [1], i.e., reactive (the…Newly identified cases of parkinsonism and prodromal PD in a remote LRRK2 G2019S cohort
Objective: To evaluate new cases of prodromal PD and concern for parkinsonism in a cohort of LRRK2 G2019S carriers. Background: LRRK2 G2019S is a common…Cortical oscillatory feature-based classification of Parkinson’s disease with freezing gait
Objective: The objective of this study was to determine the resting-state cortical oscillations and the machine learning model that best classifies Parkinson’s disease (PD) patients…Duration of continuous “Good On” intervals and number of motor fluctuations after treatment with IPX203 vs immediate-release carbidopa-levodopa in Parkinson’s disease patients with motor fluctuations.
Objective: To compare the duration of continuous “On” without troublesome dyskinesia (“Good On”) intervals and number of motor fluctuations per day in Parkinson’s disease (PD)…
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