Cholinergic Nucleus 4 Degeneration and Cognitive Impairment in REM Sleep Behavior Disorder
Objective: To determine if there is evidence of cholinergic basal forebrain degeneration, i.e., reduced cholinergic nucleus 4 (Ch4) volume on MRI, in patients with REM…Phenotypical and treatment response heterogeneity in a cohort of normal pressure hydrocephalus patients
Objective: To clinically characterize a cohort of patients with normal pressure hydrocephalus (NPH) to identify possible clinical and humoral biomarkers that can predict the response…Low-dose lithium therapy associated with increased PBMC Nurr1 and SOD1 expression in Parkinson’s disease: a pilot study.
Objective: To determine the effects of lithium therapy on blood-based biomarkers in Parkinson’s disease (PD). Background: Lithium has multiple neuroprotective actions and may account for…Relation of affective disorders and quality of life in the chronic pain of disease Parkinson’s patients
Objective: To study affective disorders and their impact on the quality of life in patients with PD and chronic pain syndrome. Background: Mechanisms of the…Clinical presentation of SNCA Duplication Parkinsonism in a Family Kindred
Objective: To report phenotype variability in a family with SNCA duplication associated Parkinsonism. Background: Pathogenic variants in SNCA, the gene coding for α-synuclein, cause familial…Awake versus Asleep Deep Brain Stimulation Lead Placement: Real-World Outcomes with Directional DBS Systems
Objective: In this report, real-world outcomes derived from Parkinson's disease (PD) patients using Deep Brain Stimulation (DBS) Systems who were implanted either awake or asleep…Geographic and Financial Trends in the Utilization of Deep Brain Stimulation in the Medicare Population from 2013-2019
Objective: To evaluate the utilization of deep brain stimulation within the Medicare population across different regions and states in the United States Background: Deep brain…Non-motor fluctuations in People with Parkinson’s considering Deep Brain Stimulation surgery
Objective: In this study we examine non-motor symptom (NMS) fluctuations reported by People with Parkinson’s (PWP) pursuing Deep Brain Stimulation (DBS) surgery using the MDS…Defining nomenclature and age cut off for Early Onset Parkinson’s Disease: Recommendations from the Early Onset Parkinson’s Disease Task Force.
Objective: To define the nomenclature for Early Onset Parkinson Disease (EOPD) / Young Onset Parkinson Disease (YOPD), and the age at onset (AAO) cut off…ADS024 attenuates striatal dopamine loss and restores movement in animal models of Parkinson’s disease
Objective: To evaluate the effect of ADS024, an oral single strain live biotherapeutic product (SS-LBP), on the pathophysiology of MPTP-induced Parkinson’s Disease (PD) phenotypes in…
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