Real-World Clinical Outcomes and Patient Experience Following Hybrid DBS Conversion to a Neurostimulator with Advanced Current Steering
Objective: In this report, we describe preliminary real-world clinical outcomes and patient experience following hybrid DBS conversion procedures at our center. Background: Hybrid replacement procedures…Progression and disability in Parkinson’s disease: what else can be done?
Objective: to identify key modifiable factors in the treatment of patients with Parkinson's disease (PD) that can slow clinical progression and disability.ity. Background: PD is…Assessment of Postural abnormalities in Early-stage Parkinson’s Disease Using a Posture Analyzing and Virtual Reconstruction Device
Objective: To investigate whether an RGB camera-based system with AI-driven analysis, the posture-analyzing and virtual reconstructing system (PAViR), can effectively assess postural abnormalities in early-stage…Subregional Striatal Dopaminergic Deficits, Cerebral Hypoperfusion and Cognitive Impairment in Parkinson’s Disease
Objective: To investigate the associations of subregional striatal dopaminergic deficits with regional cerebral blood flow (CBF) and cognitive impairment in patients with Parkinson’s disease (PD).…Implementation and Evaluation of a Pre-Clinic Questionnaire to Improve Data Capture and Consultation Efficiency in Parkinson’s Disease Clinics: A Multi-Centre Pilot Study
Objective: To evaluate the feasibility, usability, and clinical value of a pre-clinic questionnaire for patients attending Parkinson’s disease nurse specialist clinics. Background: Parkinson’s disease (PD)…Neuroprotective Effects of Curcumin on Hippocampal-PPN Circuitry in a Rotenone-Induced Rat Model of Parkinson’s Disease
Objective: This study investigated the neuroprotective effects of curcumin on the hippocampal-pedunculopontine nucleus (PPN) axis in a rotenone-induced rat model of PD. Background: Parkinson’s disease…Effects of Personalized Visual and Auditory Cueing on Sit-to-Stand Biomechanics in Individuals with Parkinson’s disease: A Subgroup Analysis
Objective: To investigate the effects of personalized visual and auditory cueing combined with task-specific sit-to-stand training on movement kinematics, functional mobility, and psychosocial outcomes in…Quantitative Analysis of Oculomotor Abnormalities in Parkinson’s Disease
Objective: To quantitatively characterize oculomotor abnormalities in patients with Parkinson’s disease (PD) and to evaluate their potential utility for assessing oculomotor dysfunction and supporting early…Rare Neurotoxicity of Cotrimoxazole A Movement Disorder Presentation In Elderly Patient
Objective: We report the case of an elderly woman with hyperkinetic movement disorders Background: Trimethoprim-sulfamethoxazole (TMP-SMX) is widely used for Pneumocystis jirovecii prophylaxis, but significant neurological toxicity…Clinical and Autonomic Correlates of Chronic Sialorrhea in Parkinson’s Disease: A Questionnaire-Based Study with Cluster Analysis of Autonomic and Dysphagia Burden
Objective: To examine factors associated with drooling in patients with Parkinson’s disease (PD), patient awareness and perceptions of botulinum toxin therapy, and the relative contributions…
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