Dopaminergic modulation of express reaching responses in Parkinson’s disease
Objective: This study investigates the role of dopamine (DA) in modulation of automatic stimulus-driven responses. We investigated the effect of PD, DA medication, and instruction…White Matter Correlates of Physical Therapy Measures in Parkinson’s disease Patients with Freezing of Gait
Objective: To identify white-matter (WM) correlates of physical therapy (PT)-measures in Parkinson’s disease (PD) patients with freezing of gait (FOG). Background: Significant gap remains in…Parkinson’s Progression Markers Initiative (PPMI) Online expands biomarker research in Parkinson’s disease (PD)
Objective: To establish a large, longitudinal online cohort linked with a selected, intensively assessed cohort of people with and without PD to characterize development and…Botulinum Toxin Therapy for Medication and DBS Refractory Foot Dystonia of Parkinsonism
Objective: To determine efficacy and safety of BTX therapy in patients with medically refractory foot dystonia secondary to Parkinson’s disease (PD) or atypical Parkinsonism (AP)…Late-onset cerebellar ataxia: case report of a new CNV on TTBK2 gene as possible cause of SCA-11
Objective: To describe a case of spinocerebellar ataxia type 11 caused by the copy number variant 43008859_43075833 on the TKKB2 gene Background: The spinocerebellar ataxias…Diagnostic Accuracy of Parkinson’s disease: Where Do We Stand?
Objective: To provide an up-to-date assessment of diagnostic accuracy parameters at early and late stages of the diagnosis in clinical practice and MDS Diagnostic Criteria…A systematic review of Movement Disorders in COVID-19
Objective: We conducted a systematic review to describe the frequency, clinical profile and outcomes of patients with SARS-CoV-2 associated movement disorders. Background: SARS-CoV-2 is associated…Application of Goal Attainment Scale as a patient-centered assessment for cervical dystonia
Objective: To explore the goal attainment scale (GAS) by interviewing the three most disturbing problems and changes after Botulinum toxin A injection in cervical dystonia…Administration of the mGlu2 positive allosteric modulator BINA as monotherapy improves parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effect of selective metabotropic glutamate type 2 (mGlu2) receptor activation on parkinsonism as monotherapy in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset compared to…DNA methylation differs between idiopathic Parkinson Disease and Healthy Control subjects in the Parkinson’s Progression Marker Initiative (PPMI) cohort
Objective: Compare baseline whole blood DNA methylation in unmedicated idiopathic Parkinson's Disease (iPD) and healthy control (HC) participants from PPMI Background: Epigenetic mechanisms like DNA…
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