Effects of Phase-Specific Vibrotactile Cueing on Spatiotemporal Gait Parameters in Parkinson’s Disease
Objective: To evaluate the effects of phase-specific vibrotactile cues applied during swing and stance phases of the gait cycle on spatiotemporal gait parameters in people…The Clinical and Biological effects of a Whole Foods and Plant-Based Dietary Intervention in Parkinson’s Disease
Objective: The Plants for Parkinson trial aims to investigate whether prolonged adherence to a plant-based and whole foods-derived dietary pattern can alleviate motor- and gastrointestinal…External Validation of a Machine Learning Classifier for Motor Progression in Parkinson’s Disease
Objective: To externally validate a previously published machine learning (ML) classifier for predicting motor symptom progression in Parkinson’s disease (PD) using an independent clinical dataset.…Probable RBD and Anxiety in Early Parkinson’s Disease Predict Subsequent Functionally Disabling Medication-Refractory Tremor
Objective: Functionally disabling, medication-refractory (FDMR) tremor is a key indication for device-aided therapy in Parkinson's disease (PD), yet baseline predictors remain poorly characterised. Background: PD…Electrophysiological Tremor Analysis In Tremor-Dominant And Postural Instability And Gait Difficulty Phenotypes Of Parkinson’s Disease
Objective: To define the differences in characteristics on electrophysiological tremor analysis between the tremor-dominant (TD) and Postural Instability and Gait Difficulty (PIGD) phenotype. Background: Based…Neuroinflammation and neurodegeneration biomarkers in Parkinson’s disease: integration of neuroimaging and fluid markers
Objective: To investigate the association between serum and cerebrospinal fluid (CSF) levels of NfL and GFAP and dopaminergic degeneration measured by 123I-ioflupane SPECT (DaTSCAN) in…FDG-PET-Based Machine Learning Differentiates Parkinson’s Disease from Other Neurodegenerative Disorders
Objective: To evaluate whether a fluorodeoxyglucose positron emission tomography (FDG-PET) machine learning (ML) framework can be extended to differentiate Parkinson's disease (PD) from other neurodegenerative…Mechanical Ventilation Modifies the Natural History of DCTN1 p.G71A Perry Disease: A 20-Year Longitudinal Study
Objective: To determine whether mechanical ventilation modifies survival and disease trajectory in an expanded Japanese pedigree with DCTN1 p.G71A–related Perry disease. Background: Perry disease is…Sex Related Differences in Parkinsons Disease Motor and Non Motor Features Treatment Response and Quality of Life
Objective: To assess sex-related differences in motor and non-motor symptoms at diagnosis, disease evolution, treatment response, and quality-of-life impact in patients with Parkinson’s disease. Background:…Patient-Defined Disease Progression in Parkinson Disease: Towards Patient-Relevant Outcome Measures
Objective: To carry out a survey on a representative sample of people with Parkinson’s (PwP) about their lived experience of a comprehensive list of Parkinson…
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