Patterns of Cortical Thinning in Patients with Parkinson’s Disease
Objective: To investigate patterns of cortical thickness that are associated with disease severity and response to levodopa. Background: Cortex affection is a neuropathological correlate of…The evaluation of the swallow tail sign in patients with parkinsonism or gait disorders
Objective: The goal of the study is to evaluate the reliability of swallow tail sign which claimed to be specific for Parkinson's disease. Background: Swallow…BASELINE OLFACTION TESTING IN PARKINSON’S DISEASE PATIENTS IS CORRELATED WITH LONG-TERM DOPAMINERGIC DENERVATION IN STRIATAL SUB-REGIONS: LONGITUDINAL DATA FROM THE PPMI STUDY.
Objective: The aim of the current study was to determine whether there are longitudinal differences in dopaminergic denervation of striatal sub-regions [signal reduction in 123I-FP-CIT…Association of presynaptic dopaminergic denervation with therapeutic effects of globus pallidus deep brain stimulation on freezing of gait in advanced Parkinson’s disease
Objective: To investigate the association of presynaptic dopaminergic denervation with the therapeutic effect of globus pallidus (GPi) DBS in advanced PD patients with FOG. Background:…Feasibility study of diffusion tensor imaging fiber tracking in PD patients after DBS operation
Objective: To explore the feasible of depicting the nigrostriatal pathway (NSP), dentate rubro thalamic (DRTT) and hyperdirect pathway (HDP) for the postoperative PD patients with…Sexual divergencies in monoaminergic projections in Parkinson’s disease: a 123I-FP-CIT SPECT study
Objective: To investigate sex differences in nigrostriatal and extrastriatal 123I-FP-CIT SPECT monoaminergic projections in healthy subjects and Parkinson’s disease (PD) Background: preclinical and clinical studies suggest…Characteristics of the amyloid beta networks in Parkinson’s disease patients: a PPMI study
Objective: The impact that amyloid beta (Aβ) accumulation in the brain has on the progression of Parkinson’s disease (PD) pathology is complex and poorly understood…Sex differences in brain and cognition in de novo PD patients
Objective: We aimed to investigate sex differences in brain atrophy and cognition in PD de novo patients through MRI subcortical volumetry and cortical thickness (CTh).…DAT-SPECT in old onset Parkinson’s disease: should we trust?
Objective: . Background: Scans without evidence of dopaminergic deficit (SWEDD) refers to patients clinically diagnosed with Parkinson’s disease (PD), but show normal findings on dopamine…Longitudinal structural and functional brain alterations in Parkinson’s disease patients with freezing of gait
Objective: To investigate the cortical/subcortical grey matter (GM) changes and network functional alterations in PD-FoG patients, in PD developing FoG (PD-FoG-converters) and PD not developing…
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