Altered functional connectivity of the hippocampus in posterior-cortical subtype of cognitive impairment in Parkinson’s disease
Objective: We aimed to delineate the dual syndrome subtypes of PD-MCI using a data-driven approach and explore hippocampal functional connectivity of the posterior-cortical syndrome. Background:…Relationship of subcortical iron deposition and mitochondrial dysfunction in patients with idiopathic Parkinson’s disease
Objective: To investigate subcortical brain iron deposition as a potential predictor of the bioenergetic status in patients with idiopathic Parkinson's disease. Background: The underlying pathophysiology…Resting state functional connectivity networks related to MDS-UPDRS motor outcomes in Parkinson’s Disease
Objective: Investigate the functional connectivity network pairs associated with the motor symptoms in people with Parkinson’s disease (pwPD). Background: PD is a neurodegenerative disorder primarily…Brain activity of the emotional circuit in Parkinson’s disease patients with freezing of gait
Objective: The aim of this observational study was to assess brain functional MRI (fMRI) activity during a “FoG observation task” in PD-FoG patients relative to…Baseline and six months change in cortical perfusion in a mesenchymal stem cell trial for Parkinson’s disease
Objective: Quantify cortical perfusion at baseline and six months after a single infusion of allogeneic bone marrow-derived mesenchymal stem cells (allo-hMSC) in relation to demographic…Progression of nigrostriatal dysfunction in Parkinson’s disease: a longitudinal multimodal PET study
Objective: To investigate the longitudinal course of nigrostriatal metabolic and dopaminergic dysfunction and its impact on symptom severity in Parkinson's disease (PD) patients using a…Dysfunctional resting connectivity in early stage of Parkinson’s disease is indistinguishable from connectivity in REM sleep behaviour disorder
Objective: To investigate the differences in functional connectivity among healthy subjects (HC), patients with REM sleep behaviour disorder (RBD) and levodopa-naïve patients in early stage…Motor symptom lateralization influences cortico-striatal functional connectivity in Parkinson’s disease
Objective: To evaluate the effect of lateralization on various cortico-striatal circuits through resting state functional MRI. Background: Striatum is unevenly impaired bilaterally in Parkinson’s disease.…Regional brain iron and gene expression variation in Parkinson’s disease
Objective: To shed light on the genes underlying increased cortical iron deposition in Parkinson’s disease (PD). Background: Oxidative stress secondary to brain iron accumulation is…VMAT2 availability in Parkinson’s Disease with Rapid Eye Movement Sleep Behaviour Disorder
Objective: To use [11C]DTBZ PET imaging to explore vesicular monoamine transporter 2 (VMAT2) availability in Parkinson’s disease (PD) with and without rapid eye movement sleep…
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