Spinal orthosis in antecollis and PISA syndrome in Parkinson.
Objective: To demonstrate the efficacy of spinal orthosis in antecollis and PISA syndrome in Parkinson patients. Background: Postural deformities in Parkinson disease (PD) including antecollis,…Denoising Local Field Potentials from Electrocardiography Artifacts
Objective: An algorithm to reliably detect and suppress the QRS complexes of the Electrocardiography (ECG) activity contaminating the Local Field Potentials (LFP) recorded via Implantable…Quantitative gait analysis using a pose-estimation algorithm with a single 2D-video of PD patients
Objective: To develop an easily accessible and objective tool to evaluate gait in PD patients, we analyzed gait from a single 2-dimensional (2D) video. Background:…Open-Source Tremor Tracking for MR-guided Focused Ultrasound (MRgFUS): An Objective Approach for Monitoring Treatments
Objective: To describe a novel system developed for real-time noninvasive monitoring of treatment efficacy in patients undergoing MR-guided Focused Ultrasound (MRgFUS) treatment for refractory tremor.…Evaluating the use of digital biomarkers to test treatment effects on cognition and motor in patients with Lewy Body Dementia
Objective: To evaluate if frequent cognitive and motor tests using an iPad app and a wrist-worn actigraphy watch to track activity and sleep can detect…Novel quantitative measures with standardised graphical tasks to objectively assess subtle changes in fine motor skill in diagnosing and monitoring of Parkinson’s disease
Objective: To integrate a handheld device with standardised graphical tasks into clinical assessment for automated objective motor symptoms rating with digital record keeping in Parkinson’s…Tissue-engineered nigrostriatal pathway to rebuild dopaminergic axons in Parkinson’s disease based on clinical design criteria
Objective: To create a tissue-engineered construct with the dopaminergic (DA) cell numbers, axon lengths, and functionality required to reconstruct the human nigrostriatal pathway (NSP). Background:…Persistent and efficient transduction of the putamen following gene therapy for aromatic L-amino acid decarboxylase deficiency
Objective: This study aimed to evaluate longitudinal transduction in subcortical regions and transduction of the cortico-putaminal network after putaminal AADC gene therapy. Background: Aromatic L-amino…The Association Between Tic Disorders and Atopy
Objective: To determine whether pediatric patients with tic disorders have an altered risk of atopy when compared with controls, whether this difference in risk is…Clinical correlates of sleep disturbances in children with Tourette syndrome
Objective: Examine potential clinical correlates of sleep disturbances in children with Tourette syndrome (TS). Background: There is increasing evidence that sleep disturbances are highly prevalent…
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